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UQCC2 Antibody

  • 货号：
    CSB-PA866268ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: UQCC2 antibody at 3.35 μg/ml
      Lane 1: HepG2 whole cell lysate
      Lane 2: 293T whole cell lysate
      Lane 3: Jurkat whole cell lysate
      Lane 4: A431 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 15 kDa
      Observed band size: 15, 40, 80 kDa
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA866268ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA866268ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) UQCC2 Polyclonal antibody
  • Uniprot No.：
    Q9BRT2
  • 基因名：
    UQCC2
  • 别名：
    UQCC2 antibody; C6orf125 antibody; MNF1 antibody; Ubiquinol-cytochrome-c reductase complex assembly factor 2 antibody; Breast cancer-associated protein SGA-81M antibody; Mitochondrial nucleoid factor 1 antibody; Mitochondrial protein M19 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Ubiquinol-cytochrome-c reductase complex assembly factor 2 protein (14-126AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Involved in cytochrome b translation and/or stability.
  • 基因功能参考文献：
    1. The function of M19, a novel mitochondrial nucleoid protein, is characterized in muscle and pancreatic beta-cells. PMID: 22363741
    2. M19 associates with the nucleoid and likely regulates the organization and metabolism of mtDNA. PMID: 19643811
  • 相关疾病：
    Mitochondrial complex III deficiency, nuclear 7 (MC3DN7)
  • 亚细胞定位：
    Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion. Mitochondrion intermembrane space. Mitochondrion matrix. Mitochondrion inner membrane.
  • 组织特异性：
    Pancreas, skeletal muscle, kidney, liver and heart.
  • 数据库链接：

    HGNC: 21237

    OMIM: 614461

    KEGG: hsa:84300

    STRING: 9606.ENSP00000363348

    UniGene: Hs.732448