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USP6NL Antibody

  • 货号：
    CSB-PA842149LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA842149LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA842149LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) USP6NL Polyclonal antibody
  • Uniprot No.：
    Q92738
  • 基因名：
    USP6NL
  • 别名：
    KIAA0019 antibody; Related to the N terminus of tre antibody; Related to the N-terminus of tre antibody; RN tre antibody; RN-tre antibody; RNTRE antibody; TRE2NL antibody; US6NL_HUMAN antibody; USP6 N terminal like antibody; USP6 N terminal like protein antibody; USP6 N-terminal-like protein antibody; USP6NL antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human USP6 N-terminal-like protein (387-693AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，USP6NL Antibody (CSB-PA842149LA01HU)，的标记方式是Non-conjugated。对于USP6NL Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA842149LB01HU USP6NL Antibody, HRP conjugated ELISA
    FITC CSB-PA842149LC01HU USP6NL Antibody, FITC conjugated
    Biotin CSB-PA842149LD01HU USP6NL Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
  • 基因功能参考文献：
    1. Genome-wide significant (GWS) associations in single-nucleotide polymorphism (SNP)-based tests (P < 5 x 10(-8)) were identified for SNPs in PFDN1/HBEGF, USP6NL/ECHDC3, and BZRAP1-AS1. PMID: 28183528
    2. Rab5 signals to the actin cytoskeleton through RN-tre, a previously identified Rab5-specific GTPase-activating protein; RN-tre interacts with both F-actin and actinin-4, an F-actin bundling protein PMID: 15152255
  • 亚细胞定位：
    Golgi apparatus. Cytoplasmic vesicle.
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 16858

    OMIM: 605405

    KEGG: hsa:9712

    STRING: 9606.ENSP00000277575

    UniGene: Hs.498661