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VARS2 Antibody

  • 货号：
    CSB-PA735951LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA735951LA01HU diluted at 1:300 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA735951LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) VARS2 Polyclonal antibody
  • Uniprot No.：
    Q5ST30
  • 基因名：
    VARS2
  • 别名：
    COXPD20 antibody; mitochondrial antibody; SYVM_HUMAN antibody; Valine--tRNA ligase antibody; ValRS antibody; Valyl tRNA synthetase 2 mitochondrial antibody; Valyl-tRNA synthetase antibody; Valyl-tRNA synthetase-like antibody; Vars2 antibody; VARS2L antibody; VARSL antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Valine--tRNA ligase, mitochondrial protein (830-981AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，VARS2 Antibody (CSB-PA735951LA01HU)，的标记方式是Non-conjugated。对于VARS2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA735951LB01HU VARS2 Antibody, HRP conjugated ELISA
    FITC CSB-PA735951LC01HU VARS2 Antibody, FITC conjugated
    Biotin CSB-PA735951LD01HU VARS2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. VARS2 mutation underlies a novel autosomal recessive syndrome with epilepsy, mental retardation, short stature, growth hormone deficiency, and hypogonadism. PMID: 29137650
    2. VARS2 polymorphism significantly associated with chronic hepatitis B in Korean population. PMID: 25404243
    3. VARS2 V552V may be considered as a prognostic factor for survival in patients with early breast cancer. PMID: 20503108
    4. Data indicate that variations in the levels of VARS2L between tissue types and patients could underlie the difference in clinical presentation between individuals homoplasmic for the 1624C>T MTTV (equivalent to mt-tRNAVal C25U) mutation. PMID: 18400783
  • 相关疾病：
    Combined oxidative phosphorylation deficiency 20 (COXPD20)
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Class-I aminoacyl-tRNA synthetase family
  • 数据库链接：

    HGNC: 21642

    OMIM: 612802

    KEGG: hsa:57176

    STRING: 9606.ENSP00000441000

    UniGene: Hs.597526