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VEZT Antibody

  • 货号：
    CSB-PA025846GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9HBM0
  • 基因名：
    VEZT
  • 别名：
    VEZT; Vezatin
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human VEZT
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. Required for morphogenesis of the preimplantation embryo, and for the implantation process.; (Microbial infection) In case of Listeria infection, promotes bacterial internalization by participating in myosin VIIa recruitment to the entry site.
  • 基因功能参考文献：
    1. This study identified the most effective small activating RNA via real-time PCR and Western blot. The selected small activating RNA inhibited the growth, invasion and migration of gastric cancer cells by specially reactivating VEZT. PMID: 27856244
    2. VEZT expression levels can be considered as a biomarker for gastric cancer progression, lymphatic metastasis and as a novel independent prognostic factor. PMID: 25792470
    3. vezatin and nearby SNP rs10859871 may have a role in endometriosis [meta-analysis] PMID: 25678572
    4. VEZT, a novel putative tumor suppressor, suppresses the growth and tumorigenicity of gastric cancer. PMID: 24069310
    5. function of mouse vezatin in mouse blastocyst morphogenesis PMID: 16199027
    6. miR-43c directly targets adherens junctions' transmembrane protein (VEZT) and suppresses VEZT protein expression. PMID: 21156161

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  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Cell projection, stereocilium membrane. Cell junction, adherens junction. Nucleus. Cytoplasmic vesicle, secretory vesicle, acrosome.
  • 蛋白家族：
    Vezatin family
  • 数据库链接：

    HGNC: 18258

    KEGG: hsa:55591

    STRING: 9606.ENSP00000410083

    UniGene: Hs.24135