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VWA1 Antibody

  • 中文名称：
    VWA1兔多克隆抗体
  • 货号：
    CSB-PA025950GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q6PCB0
  • 基因名：
    VWA1
  • 别名：
    von Willebrand factor A domain-containing protein 1 antibody; VWA1 antibody; VWA1_HUMAN antibody; WARP antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human VWA1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Promotes matrix assembly.
  • 基因功能参考文献：
    1. Our results reveal the molecular mechanism of collagen-regulated, A1-mediated platelet adhesion enhancement. PMID: 26213126
    2. The VWA1 domain of matrilin-3 is primarily responsible for the induction of IL-6 release from primary human chondrocytes. PMID: 23523902
    3. WARP is ideally placed to function as an adapter protein in the cartilage pericellular matrix. PMID: 23300779
    4. The distinct localization of WARP in the human and mouse inner ear blood vessels suggests an important role maintaining the integrity of the vasculature. PMID: 20971096
    5. Evolutionary relationship between von Willebrand factor A domain-related protein (WARP), and the fibril-associated collagen with interrupted triple helix (FACIT) and FACIT-like subfamilies of collagens. PMID: 14527666
    6. WARP forms macromolecular structures that interact with perlecan to contribute to the assembly and/or maintenance of "permanent" cartilage structures during development and in mature cartilages PMID: 16407285
    7. Urea was used as a surrogate for shear to study denaturation of the individual VWF recombinant A domains, A1, A2, and A3, and the domain triplet, A1-A2-A3. PMID: 17187823

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  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix, basement membrane.
  • 数据库链接：

    HGNC: 30910

    OMIM: 611901

    KEGG: hsa:64856

    STRING: 9606.ENSP00000417185

    UniGene: Hs.449009