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WBSCR17 Antibody

  • 货号：
    CSB-PA025982GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q6IS24
  • 基因名：
    GALNT17
  • 别名：
    GALNT17 antibody; WBSCR17Polypeptide N-acetylgalactosaminyltransferase 17 antibody; EC 2.4.1.41 antibody; Polypeptide GalNAc transferase-like protein 3 antibody; GalNAc-T-like protein 3 antibody; pp-GaNTase-like protein 3 antibody; Protein-UDP acetylgalactosaminyltransferase-like protein 3 antibody; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3 antibody; Williams-Beuren syndrome chromosomal region 17 protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human WBSCR17
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
  • 基因功能参考文献：
    1. GWA study identified maternal genetic effects not previously identified in ASD at a locus in WBSCR17. PMID: 27876814
    2. a subset of O-glycosylation produced by WBSCR17 controls dynamic membrane trafficking, probably between the cell surface and the late endosomes through macropinocytosis PMID: 22787146
  • 相关疾病：
    WBSCR17 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 组织特异性：
    Highly expressed in brain and heart. Weakly expressed in kidney, liver, lung and spleen.
  • 数据库链接：

    HGNC: 16347

    OMIM: 615137

    KEGG: hsa:64409

    STRING: 9606.ENSP00000329654

    UniGene: Hs.488591