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WDFY1 Antibody

  • 中文名称：
    WDFY1兔多克隆抗体
  • 货号：
    CSB-PA816890LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: RAW264.7 whole cell lysate, THP-1 whole cell lysate, Mouse Brain tissue lysate, Mouse Liver tissue lysate, Mouse Kidney tissue lysate
      All lanes: WDFY1 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 47 kDa
      Observed band size: 47 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) WDFY1 Polyclonal antibody
  • Uniprot No.：
    Q8IWB7
  • 基因名：
    WDFY1
  • 别名：
    FENS 1 antibody; FENS-1 antibody; FENS1 antibody; KIAA1435 antibody; Phosphoinositide binding protein 1 antibody; Phosphoinositide binding protein SR1 antibody; Phosphoinositide-binding protein 1 antibody; WD repeat and FYVE domain containing 1 antibody; WD repeat and FYVE domain-containing protein 1 antibody; WD40 and FYVE domain containing protein 1 antibody; WD40- and FYVE domain-containing protein 1 antibody; WDF1 antibody; WDFY1 antibody; WDFY1_HUMAN antibody; ZFYVE17 antibody; Zinc finger FYVE domain containing protein 17 antibody; Zinc finger FYVE domain-containing protein 17 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human WD repeat and FYVE domain-containing protein 1 protein (261-357AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，WDFY1 Antibody (CSB-PA816890LA01HU)，的标记方式是Non-conjugated。对于WDFY1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA816890LB01HU WDFY1 Antibody, HRP conjugated ELISA
    FITC CSB-PA816890LC01HU WDFY1 Antibody, FITC conjugated
    Biotin CSB-PA816890LD01HU WDFY1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines.
  • 基因功能参考文献：
    1. NRP2 inhibits WDFY1 transcription by preventing the nuclear localization of a transcription factor, Fetal ALZ50-reactive clone 1 (FAC1). PMID: 27026195
    2. WDFY1 mediates TLR3/TLR4 signaling by recruiting TRIF. PMID: 25736436
  • 亚细胞定位：
    Early endosome.
  • 数据库链接：

    HGNC: 20451

    KEGG: hsa:57590

    STRING: 9606.ENSP00000233055

    UniGene: Hs.368359