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WDR59 Antibody

  • 货号：
    CSB-PA764810LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of U251 cells with CSB-PA764810LA01HU at 1:173, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Western Blot
      Positive WB detected in: 293T whole cell lysate, MCF-7 whole cell lysate, 293 whole cell lysate
      All lanes: WDR59 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 110, 65, 63, 47 kDa
      Observed band size: 110 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) WDR59 Polyclonal antibody
  • Uniprot No.：
    Q6PJI9
  • 基因名：
  • 别名：
    WDR59 antibody; KIAA1923 antibody; FP977 antibody; GATOR complex protein WDR59 antibody; WD repeat-containing protein 59 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human GATOR complex protein WDR59 protein (619-862AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，WDR59 Antibody (CSB-PA764810LA01HU)，的标记方式是Non-conjugated。对于WDR59 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA764810LB01HU WDR59 Antibody, HRP conjugated ELISA
    FITC CSB-PA764810LC01HU WDR59 Antibody, FITC conjugated
    Biotin CSB-PA764810LD01HU WDR59 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.
  • 亚细胞定位：
    Lysosome membrane.
  • 蛋白家族：
    WD repeat WDR59 family
  • 数据库链接：

    HGNC: 25706

    OMIM: 617418

    KEGG: hsa:79726

    STRING: 9606.ENSP00000262144

    UniGene: Hs.280951