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XPR1 Antibody

  • 货号：
    CSB-PA871381LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA871381LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA871381LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA871381LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) XPR1 Polyclonal antibody
  • Uniprot No.：
    Q9UBH6
  • 基因名：
    XPR1
  • 别名：
    FLJ90308 antibody; OTTHUMP00000033084 antibody; OTTHUMP00000033085 antibody; Polytropic murine leukamia virus receptor SYG 1 antibody; Polytropic murine leukamia virus receptor SYG1 antibody; Protein SYG1 homolog antibody; SYG 1 antibody; SYG1 antibody; SYG1 protein antibody; X-receptor antibody; X3 antibody; Xenotropic and polytropic murine leukemia virus receptor X3 antibody; Xenotropic and polytropic retrovirus receptor antibody; Xenotropic and polytropic retrovirus receptor 1 antibody; XPR 1 antibody; XPR1 antibody; XPR1 protein antibody; XPR1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Xenotropic and polytropic retrovirus receptor 1 protein (529-696AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，XPR1 Antibody (CSB-PA871381LA01HU)，的标记方式是Non-conjugated。对于XPR1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA871381LB01HU XPR1 Antibody, HRP conjugated ELISA
    FITC CSB-PA871381LC01HU XPR1 Antibody, FITC conjugated
    Biotin CSB-PA871381LD01HU XPR1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in phosphate homeostasis. Mediates phosphate export from the cell. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules.
  • 基因功能参考文献：
    1. These results confirm that loss of XPR1-mediated phosphate export function causes primary familial brain calcification, occurring in less than 8 % of cases negative for the other genes, and may be responsible for parkinsonism. PMID: 27230854
    2. XPR1 mutations alter phosphate export and phosphate homeostasis in primary familial brain calcification. PMID: 25938945
    3. These studies suggest that the expression of Xpr1 and certain genotypes of the RNASEL gene, which could restrict XMRV infection, may play important roles in defining XMRV tropisms in certain cell types. PMID: 20410264
  • 相关疾病：
    Basal ganglia calcification, idiopathic, 6 (IBGC6)
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    SYG1 (TC 2.A.94) family
  • 组织特异性：
    Widely expressed. Detected in spleen, lymph node, thymus, leukocytes, bone marrow, heart, kidney, pancreas and skeletal muscle.
  • 数据库链接：

    HGNC: 12827

    OMIM: 605237

    KEGG: hsa:9213

    STRING: 9606.ENSP00000356562

    UniGene: Hs.227656