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YAF2 Antibody

  • 货号：
    CSB-PA810297LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA810297LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human glioma using CSB-PA810297LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) YAF2 Polyclonal antibody
  • Uniprot No.：
    Q8IY57
  • 基因名：
    YAF2
  • 别名：
    MGC41856 antibody; YAF2 antibody; YAF2_HUMAN antibody; YY1-associated factor 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human YY1-associated factor 2 protein (1-204AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，YAF2 Antibody (CSB-PA810297LA01HU)，的标记方式是Non-conjugated。对于YAF2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA810297LB01HU YAF2 Antibody, HRP conjugated ELISA
    FITC CSB-PA810297LC01HU YAF2 Antibody, FITC conjugated
    Biotin CSB-PA810297LD01HU YAF2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.
  • 基因功能参考文献：
    1. These findings uncovered an apoptotic signaling cascade linking YAF2, PDCD5, and TP53 during genotoxic stress responses. PMID: 25603536
    2. YEAF1/RYBP and YAF-2 are functionally distinct members of a cofactor family for the YY1 and E4TF1/hGABP transcription factors. PMID: 11953439
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 17363

    OMIM: 607534

    KEGG: hsa:10138

    UniGene: Hs.649195