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ZBTB46 Antibody

  • 货号：
    CSB-PA803124HA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: ZBTB46 antibody at 2μg/ml
      Lane 1: Mouse heart tissue
      Lane 2: Mouse liver tissue
      Lane 3: Mouse kidney tissue
      Lane 4: 293T whole cell lysate
      Lane 5: SH-SY5Y whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 65 kDa
      Observed band size: 65 kDa
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA803124HA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA803124HA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品描述：

    The ZBTB46 antibody is raised in the rabbit against a partial protein corresponding to 174-362 amnio acids of the human ZBTB46 protein. It is available as the unconjugated IgG isoform. Its purity is 95%+ using protein G purified. This antibody is reactive to human and mouse ZBTB46 protein. And it has been quality control tested in ELISA, WB, and IHC applications. Its target protein ZBTB46 is highly expressed in quiescent endothelial cells and functions as a shear-sensitive transcription factor suppressing endothelial cell proliferation through the expression regulation of cell cycle proteins.

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ZBTB46 Polyclonal antibody
  • Uniprot No.：
    Q86UZ6
  • 基因名：
    ZBTB46
  • 别名：
    ZBTB46 antibody; BTBD4 antibody; ZNF340 antibody; Zinc finger and BTB domain-containing protein 46 antibody; BTB-ZF protein expressed in effector lymphocytes antibody; BZEL antibody; BTB/POZ domain-containing protein 4 antibody; Zinc finger protein 340 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Zinc finger and BTB domain-containing protein 46 protein (174-362AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ZBTB46 Antibody (CSB-PA803124HA01HU)，的标记方式是Non-conjugated。对于ZBTB46 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA803124HB01HU ZBTB46 Antibody, HRP conjugated ELISA
    FITC CSB-PA803124HC01HU ZBTB46 Antibody, FITC conjugated
    Biotin CSB-PA803124HD01HU ZBTB46 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions as a transcriptional repressor for PRDM1.
  • 基因功能参考文献：
    1. s report a novel tumor promoter, ZBTB46, which is negatively regulated by AR signaling via microRNA (miR)-1-mediated downregulation. ZBTB46 is associated with malignant prostate cancer and is essential for metastasis. PMID: 28692046
    2. A single nucleotide polymorphisn in ZBTB46, rs6062314, is associated with an increased genetic risk for multiple sclerosis. PMID: 23739915
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 16094

    OMIM: 614639

    KEGG: hsa:140685

    STRING: 9606.ENSP00000245663

    UniGene: Hs.585028