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ZFAND6 Antibody

  • 货号：
    CSB-PA739009HA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA739009HA01HU at dilution of 1:100
    • Immunofluorescent analysis of A549 cells using CSB-PA739009HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ZFAND6 Polyclonal antibody
  • Uniprot No.：
    Q6FIF0
  • 基因名：
    ZFAND6
  • 别名：
    ZFAND6 antibody; AWP1 antibody; ZA20D3 antibody; HT032 antibody; AN1-type zinc finger protein 6 antibody; Associated with PRK1 protein antibody; Zinc finger A20 domain-containing protein 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human AN1-type zinc finger protein 6 protein (1-208AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ZFAND6 Antibody (CSB-PA739009HA01HU)，的标记方式是Non-conjugated。对于ZFAND6 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA739009HB01HU ZFAND6 Antibody, HRP conjugated ELISA
    FITC CSB-PA739009HC01HU ZFAND6 Antibody, FITC conjugated
    Biotin CSB-PA739009HD01HU ZFAND6 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes.
  • 基因功能参考文献：
    1. ZFAND6 was identified as a type 2 diabetes susceptibility gene. ZFAND6 plays a role in insulin secretion in vitro. PMID: 28580277
    2. By observing the data obtained from the isothermal titration calorimetry assay, both of the human proteins (KRCC1 and ZFAND6) were demonstrated to bind to their respective Toxoplasma gondii SAG1 and SAG2 proteins. PMID: 29351065
    3. The AN1 domain of AWP1 mediated the functional interaction with tumor necrosis factor receptor-associated factor 2, and the A20 domain was responsible for the negative regulation of nuclear factor kappaB activation. PMID: 21810480
  • 亚细胞定位：
    Cytoplasm.
  • 组织特异性：
    Widely expressed with high level in heart, skeletal muscle, liver, kidney and placenta.
  • 数据库链接：

    HGNC: 30164

    OMIM: 610183

    KEGG: hsa:54469

    STRING: 9606.ENSP00000261749

    UniGene: Hs.596679