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ZNF281 Antibody

  • 货号：
    CSB-PA026637LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA026637LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ZNF281 Polyclonal antibody
  • Uniprot No.：
    Q9Y2X9
  • 基因名：
    ZNF281
  • 别名：
    GC box binding zinc finger protein 1 antibody; GC-box-binding zinc finger protein 1 antibody; GZP1 antibody; Transcription factor ZBP-99 antibody; ZBP 99 antibody; ZBP99 antibody; zfp281 antibody; Zinc finger DNA binding protein 99 antibody; Zinc finger DNA-binding protein 99 antibody; Zinc finger protein 281 antibody; ZN281_HUMAN antibody; ZNF281 antibody; ZNP 99 antibody; ZNP 99 transcription factor antibody; ZNP99 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Zinc finger protein 281 protein (1-300AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ZNF281 Antibody (CSB-PA026637LA01HU)，的标记方式是Non-conjugated。对于ZNF281 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA026637LB01HU ZNF281 Antibody, HRP conjugated ELISA
    FITC CSB-PA026637LC01HU ZNF281 Antibody, FITC conjugated
    Biotin CSB-PA026637LD01HU ZNF281 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs. Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.
  • 基因功能参考文献：
    1. These observations suggest that ZNF281 is a controller of neuronal differentiation that should be evaluated as a prognostic marker in neuroblastoma. PMID: 29941555
    2. involvement of ZNF281 in the cellular response to genotoxic stress through the control exercised on the expression of genes that act in different repair mechanisms PMID: 26300006
    3. High ZNF281 expression is associated with colon and breast cancer. PMID: 24185900
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 数据库链接：

    HGNC: 13075

    KEGG: hsa:23528

    STRING: 9606.ENSP00000294740

    UniGene: Hs.59757