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ZNF408 Antibody

  • 货号：
    CSB-PA026728LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA026728LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ZNF408 Polyclonal antibody
  • Uniprot No.：
    Q9H9D4
  • 基因名：
    ZNF408
  • 别名：
    EVR6 antibody; PFM14 antibody; PR domain zinc finger protein 17 antibody; PRDM17 antibody; RP72 antibody; Zinc finger protein 408 antibody; ZN408_HUMAN antibody; ZNF408 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Zinc finger protein 408 protein (317-635AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ZNF408 Antibody (CSB-PA026728LA01HU)，的标记方式是Non-conjugated。对于ZNF408 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA026728LB01HU ZNF408 Antibody, HRP conjugated ELISA
    FITC CSB-PA026728LC01HU ZNF408 Antibody, FITC conjugated
    Biotin CSB-PA026728LD01HU ZNF408 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in transcriptional regulation.
  • 基因功能参考文献：
    1. This is the first study to report a group of patients with digenic familial exudative vitreoretinopathy (FEVR). In most affected eyes, the stage was more severe than stage 3. We speculate that the phenotype of FEVR is more severe in patients with digenic rather than monogenic variants of FEVR-related genes. PMID: 30097784
    2. In conclusion, we report a novel mutation in ZNF408 causing autosomal recessive retinitis pigmentosa with vitreal alterations in three members of a Tunisian family, which further accentuates the role of this new gene in the susceptibility to retinitis pigmentosa. PMID: 28095122
    3. Several novel mutations (missense, non-stop and insertion) were detected in the coding regions of FZD4, TSPAN12 and ZNF408 genes among the unrelated vitreoretinopathy probands. PMID: 27316669
    4. ZNF408, previously associated with Familial Exudative Vitreoretinopathy (FEVR), is a new gene causing autosomal recessive rtinitis pigmentosa. PMID: 25882705
    5. Data indicate ZNF408 missense variant (p.Ser126Asn) in 132 familial exudative vitreoretinopathy (FEVR) individuals in a Japanese family. PMID: 23716654

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  • 相关疾病：
    Vitreoretinopathy, exudative 6 (EVR6); Retinitis pigmentosa 72 (RP72)
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Highest expression is observed in adult retina; abundantly expressed in the fetal eye. In the retina, it is detected in the outer nuclear layer, especially cone and rod photoreceptor cells, ganglion cell layer and both outer and inner plexiform layers (at
  • 数据库链接：

    HGNC: 20041

    OMIM: 616454

    KEGG: hsa:79797

    STRING: 9606.ENSP00000309606

    UniGene: Hs.656931