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ampC Antibody

  • 货号：
    CSB-PA326492HA01EZX
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品描述：
    ampC polyclonal antibody CSB-PA326492HA01EZX was produced in the rabbit immunized by using the Recombinant Pseudomonas aeruginosa Beta-lactamase protein (27-397AA) as the immunogen. The target protein ampC belongs to class-C beta-lactamase family. Expression of ampC is partially controlled by a regulatory factor, AmpR, which represses transcription in wild-type cells. Induction of ampC also requires the presence of two other proteins, the AmpG permease and AmpD amidase, and the induction process is intimately linked to the cell wall recycling pathway.
    This Rabbit anti-Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) ampC Polyclonal antibody was tested in the ELISA. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It reacts with the ampC proteins of pseudomonas aeruginosa -origin and may be used to detect the endogenous levels of ampC protein.
  • 产品名称：
    Rabbit anti-Pseudomonas aeruginosa ampC Polyclonal antibody
  • Uniprot No.：
    P24735
  • 基因名：
    ampC
  • 别名：
    ampC antibody; PA4110Beta-lactamase antibody; EC 3.5.2.6 antibody; Cephalosporinase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Pseudomonas aeruginosa
  • 免疫原：
    Recombinant Pseudomonas aeruginosa Beta-lactamase protein (27-397AA)
  • 免疫原种属：
    Pseudomonas aeruginosa
  • 标记方式：
    Non-conjugated

    本页面中的产品，ampC Antibody (CSB-PA326492HA01EZX)，的标记方式是Non-conjugated。对于ampC Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA326492HB01EZX ampC Antibody, HRP conjugated ELISA
    FITC CSB-PA326492HC01EZX ampC Antibody, FITC conjugated
    Biotin CSB-PA326492HD01EZX ampC Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Among several acquired beta-lactamase enzymes, the blaPER-1 and blaVEB-1, although produced less frequently, have clinical importance because of conferring resistance to oxyimino beta-lactams. PMID: 26944896
    2. Changes have been identified within AmpD responsible for derepression of ampC and conferring ceftazidime resistance. PMID: 27067331
    3. Pseudomonas aeruginosa is able to adapt to efficacious beta-lactams, including the newer cephalosporin ceftolozane, through a variety of mutations affecting its intrinsic beta-lactamase, AmpC. PMID: 26248364
    4. Overexpression of the ampC gene was observed in carbapenem-resistant P. aeruginosa isolates, but no carbapenem-susceptible isolates overexpressed the ampC gene. PMID: 22633564
  • 亚细胞定位：
    Periplasm.
  • 蛋白家族：
    Class-C beta-lactamase family
  • 数据库链接：

    KEGG: pae:PA4110

    STRING: 208964.PA4110