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bamB Antibody

  • 货号：
    CSB-PA300609XA11ENV
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: bamB Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 31 kDa
      Observed band size: 31 kDa
  • 其他：

产品详情

  • Uniprot No.：
    P77774
  • 基因名：
    bamB
  • 别名：
    Outer membrane protein assembly factor BamB, bamB, yfgL
  • 反应种属：
    E.coli
  • 免疫原：
    Recombinant E.coli bamB protein (125-386aa)
  • 免疫原种属：
    Escherichia coli(strain K12)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Affinity-chromatography
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex, which may orient the flexible periplasmic domain of BamA for interaction with other Bam components, chaperones and nascent outer membrane proteins. Efficient substrate folding and insertion into the outer membrane requires all 5 subunits. A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly complete Bam complexes show there is considerable movement of all 5 proteins.
  • 基因功能参考文献：
    1. The crystal structure shows that BamB has an eight-bladed beta-propeller structure, with four beta-strands making up each blade. PMID: 21168416
    2. BamB could simultaneously bind to BamA and prefolded beta-barrel proteins, thereby enhancing the folding and membrane insertion capability of the Bam complex. PMID: 21236263
    3. A yfgL- negative isogenic mutant showed a marked decrease both in its ability to invade Intestine-407 cells and in the amount of the outer membrane proteins OmpA and OmpC. PMID: 15774871
    4. YfgL is part of a multiprotein complex involved in the assembly of outer membrane beta barrel proteins PMID: 15851036
    5. The data presented here suggest that the yfgL effect on outer membrane proteins also stems from a defective assembly apparatus, leading to aberrant outer membrane protein assembly, except for TolC PMID: 17015657
    6. The periplasmic phosphoquinolipoprotein kinase YfgL plays an important role in radiation-induced DNA strand break repair and homologous recombination in E. coli. PMID: 17630970
    7. Report show that the region of YfgL encompassing L173, L175, and R176 makes direct contact with YaeT and that altering residues D227 and D229 in another region of YfgL from E221 to D229 resulted in defective YaeT bindings. PMID: 18165306

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  • 亚细胞定位：
    Cell outer membrane; Lipid-anchor.
  • 蛋白家族：
    BamB family
  • 数据库链接：

    KEGG: ecj:JW2496

    STRING: 316385.ECDH10B_2678