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dnaQ Antibody

  • 货号：
    CSB-PA360933XA01ENV
  • 规格：
    ￥880
  • 图片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:dnaQ Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 29.4 kDa
      Observed band size: 30 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Escherichia coli (strain K12) dnaQ Antibody Polyclonal antibody
  • Uniprot No.：
    P03007
  • 基因名：
    dnaQ Antibody
  • 别名：
    DNA polymerase III subunit epsilon (EC 2.7.7.7) dnaQ mutD b0215 JW0205
  • 宿主：
    Rabbit
  • 反应种属：
    Escherichia coli (strain K12)
  • 免疫原：
    Recombinant Escherichia coli (strain K12) dnaQ protein (1-243aa)
  • 免疫原种属：
    Escherichia coli (strain K12)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease. Contacts both the beta sliding clamp (dnaN) and the polymerase subunit (dnaE), stabilizing their interaction.
  • 基因功能参考文献：
    1. Loss of the 3' proofreading exonuclease activity of the replicative DNA polymerase III greatly elevates quasipalindrome-associated mutagenesis. PMID: 28605670
    2. evidence that hydrophobic interactions have a predominant contribution to the stability of the complex and that the association of epsilon186 with theta stabilized epsilon186 PMID: 15459336
    3. Data shows that the proofreading domain of epsilon subunit is connected to the alpha subunit via a flexible linker peptide comprising over 20 residues. PMID: 18663010
  • 数据库链接：

    KEGG: ecj:JW0205

    STRING: 316385.ECDH10B_0196