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fimA Antibody

  • 货号：
    CSB-PA361210ZA01ENV
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: fimA antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 31.8 kDa
      Observed band size: 36 kDa
  • 其他：

产品详情

  • 产品描述：

    Rabbit polyclonal antibody against fimA is developed in a rabbit. The peptide sequence for the immunogen was taken from within the amino acids 24-182 of the recombinant Escherichia coli fimA protein. This fimA antibody is purified by protein A/G. Two applications ELISA and WB have been used in assays to test for the specificity of this fimA antibody.

    fimA is necessary for the assembly and stability of type 1 fimbriae. It has been implicated in other bacterial functions, such as bacterial aggregation, bacterial growth and survival in different environments, and bacterial virulence. Mutations in the fimA gene can result in the loss of fimbrial expression or altered fimbrial structure.

  • Uniprot No.：
    P04128
  • 基因名：
    fimA
  • 别名：
    Type-1 fimbrial protein, A chain (Type-1A pilin), fimA, pilA
  • 反应种属：
    Cassava brown streak virus
  • 免疫原：
    Recombinant Escherichia coli Type-1 fimbrial protein, A chain (fimA) (24-182AA)
  • 免疫原种属：
    Escherichia coli (strain K12)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Protein G
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.
  • 基因功能参考文献：
    1. FimA is capable of intramolecular self-complementation via its own donor strand, as evidenced by the loss of folding competence upon donor strand deletion. PMID: 21816158
    2. Results show that pilA recombinant protein has some immunoprotection effect with the challenging of virulent strains of E. coli GH1.2. PMID: 17577990
    3. report the identification of a soluble form of the pilus protein FimA from the culture supernatants of E. coli K1, Salmonella, and Shigella that can potently inhibit Bax-mediated release of cytochrome c from isolated mitochondria. PMID: 20347420
  • 亚细胞定位：
    Fimbrium.
  • 蛋白家族：
    Fimbrial protein family
  • 数据库链接：

    KEGG: ecj:JW4277

    STRING: 316407.85677057