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flu Antibody

  • 货号：
    CSB-PA336540XA01ENV
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: flu antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 42 kDa
      Observed band size: 42 kDa
  • 其他：

产品详情

  • Uniprot No.：
    P39180
  • 基因名：
    flu
  • 别名：
    Antigen 43 (AG43) (Fluffing protein) [Cleaved into: Antigen 43 alpha chain; Antigen 43 beta chain] flu yeeQ yzzX b2000 JW1982
  • 反应种属：
    Escherichia coli (strain K12)
  • 免疫原：
    Recombinant Escherichia coli (strain K12) flu protein (804-1039aa )
  • 免疫原种属：
    Escherichia coli (strain K12)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Protein G
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Controls colony form variation and autoaggregation. May function as an adhesin.
  • 基因功能参考文献：
    1. In the K-12 leader sequence, two in-frame translation initiation codons have been identified, one upstream and the other downstream of the transcription terminator. For optimal agn43 expression, both codons need to be present. PMID: 24837285
    2. Lrp and MqsR, previously identified as agn43 regulators, do not regulate agn43 expression or ON/OFF switch frequency. PMID: 24039985
    3. The data support a model in which in an ON-phase cell, the subcellular OxyR availability at the replication fork as it passes through the agn43 regulatory region is key for initiating an ON-to-OFF switch. PMID: 20118257
    4. glycosylated form of Ag43 enhances bacterial binding to human cell lines PMID: 16484190
    5. In vivo, the H107A substitution in sigma(32) impedes recovery from heat shock (exposure to 42 degrees C), and it also leads to overexpression at lower temperatures (30 degrees C) of the Flu protein, which is associated with biofilm formation PMID: 17921304
    6. that glycosylation may play significant roles in structural and functional properties of bacterial autotransporters Ag43 at many different levels. PMID: 18341480
    7. Proposed roles of Ag43 expression are summarized and the studies are put into perspective regarding the role of allelic variants, genetic background of the bacterial strain, and control of expression by phase variation. Review. PMID: 18785838
    8. The s show that Ag43 mediates bacterial adhesion in a cell line-specific manner and that structural variations of the alpha(43) domain correlate with increased adhesive properties to proteins of the extracellular matrix such as collagen and laminin. PMID: 19230760

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  • 亚细胞定位：
    [Antigen 43]: Periplasm.; [Antigen 43 alpha chain]: Secreted. Cell surface. Note=The cell surface component is about 60 kDa and can be released by mild heat treatment (PubMed:22466966).; [Antigen 43 beta chain]: Cell outer membrane; Multi-pass membrane protein. Note=May form a beta-barrel.
  • 数据库链接：

    KEGG: ecj:JW1982

    STRING: 316385.ECDH10B_2146