gH Antibody
产品详情
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产品描述:
The recombinant human cytomegalovirus (hCMV) envelope glycoprotein H (gH) protein (24-195AA) is used to immunize rabbits to generate the anti-gH antibody. The resulting antibody is a polyclonal antibody and exists as an unconjugated IgG. It is purified by protein G and reaches up to 95% in purity. And it only reacts with the hCMV sample. The target protein gH is a component of the hCMV glycoprotein complex and dimerizes with gL to form the heterodimer gH-gL that is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. This gH antibody is suitable for the detection of gH protein in ELISA analysis.
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产品名称:Rabbit anti-Human cytomegalovirus gH Polyclonal antibody
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Uniprot No.:P12824
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基因名:gH
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别名:gH antibody; UL75 antibody; Envelope glycoprotein H antibody; gH antibody
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宿主:Rabbit
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反应种属:Human cytomegalovirus
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免疫原:Recombinant Human cytomegalovirus Envelope glycoprotein H protein (24-195AA)
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免疫原种属:Human cytomegalovirus
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标记方式:Non-conjugated
本页面中的产品,gH Antibody (CSB-PA319015LA01HWV),的标记方式是Non-conjugated。对于gH Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA. The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2.
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亚细胞定位:Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein.
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蛋白家族:Herpesviridae glycoprotein H family
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