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otop1 Antibody

  • 货号：
    CSB-PA773835XA01DIL
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: otop1 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 31 kDa
      Observed band size: 31 kDa
  • 其他：

产品详情

  • Uniprot No.：
    Q7ZWK8
  • 基因名：
    otop1
  • 别名：
    Otopetrin-1 otop1
  • 反应种属：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 免疫原：
    Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) otop1 protein (406-518aa)
  • 免疫原种属：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Affinity-chromatography
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. May be involved in sour taste perception in sour taste cells by mediating entry of protons within the cytosol.
  • 基因功能参考文献：
    1. Otopetrin 1 in zebrafish may be involved in the protein trafficking of components required for formation of biominerals in the ear. PMID: 15480759
    2. Results demonstrate that otopetrin 1 has an essential and conserved role in the timing of formation and the size and shape of the developing otolith. PMID: 15581873
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Otopetrin family
  • 数据库链接：

    KEGG: dre:322893

    UniGene: Dr.77257