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prn Antibody

  • 货号：
    CSB-PA321224LA01BUA
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品描述：

    The CSB-PA321224LA01BUA polyclonal antibody against prn was generated in rabbits through immunization with the recombinant Bordetella pertussis Pertactin autotransporter protein (632-910aa). The prn protein is an agglutinogen that binds to eukaryotic cells, facilitated by the R-G-D sequence, and is potentially involved in bacterial adhesion, contributing to the virulence of the organism. It is synthesized only in the presence of low Mg2+ concentration and may play a role in the development of whooping cough.

    The purified rabbit anti-Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) prn polyclonal antibody exhibited a 95% purity level following protein G purification. This non-conjugated IgG specifically reacts with the prn proteins of Bordetella pertussis origin and is suitable for detecting endogenous levels of prn protein, as tested in ELISA.

  • 产品名称：
    Rabbit anti-Bordetella pertussis prn Polyclonal antibody
  • Uniprot No.：
    P14283
  • 基因名：
    prn
  • 别名：
    prn antibody; omp69A antibody; BP1054 antibody; Pertactin autotransporter antibody; P.93) [Cleaved into: Outer membrane protein P.69; Pertactin translocator] antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Bordetella pertussis
  • 免疫原：
    Recombinant Bordetella pertussis Pertactin autotransporter protein (632-910AA)
  • 免疫原种属：
    Bordetella pertussis
  • 标记方式：
    Non-conjugated

    本页面中的产品，prn Antibody (CSB-PA321224LA01BUA)，的标记方式是Non-conjugated。对于prn Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA321224LB01BUA prn Antibody, HRP conjugated ELISA
    FITC CSB-PA321224LC01BUA prn Antibody, FITC conjugated
    Biotin CSB-PA321224LD01BUA prn Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Agglutinogen that binds to eukaryotic cells; a process mediated by the R-G-D sequence. Pertactin may have a role in bacterial adhesion, and thus play a role in virulence. May contribute to the disease state of whooping cough.
  • 基因功能参考文献：
    1. Prn-KO strains induced an increased production of pro-inflammatory cytokines by human and murine dendritic cell. PMID: 29559630
    2. Multiple driving forces required for efficient secretion of autotransporter virulence proteins, such as pertactin. PMID: 25670852
    3. Results indicate that the purified pertactin is a potential candidate as immunogen for preparation of diagnostic reagents and as a vaccine component. PMID: 20306653
  • 亚细胞定位：
    [Pertactin autotransporter]: Periplasm.; [Outer membrane protein P.69]: Secreted. Cell surface.; [Pertactin translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
  • 数据库链接：

    KEGG: bpe:BP1054

    STRING: 257313.BP1054