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vacA Antibody

  • 货号：
    CSB-PA345927LA01B2M
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Helicobacter pylori vacA Polyclonal antibody
  • Uniprot No.：
    P55981
  • 基因名：
    vacA
  • 别名：
    vacA antibody; HP_0887 antibody; Vacuolating cytotoxin autotransporter [Cleaved into: Vacuolating cytotoxin; Vacuolating cytotoxin translocator] antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Helicobacter pylori
  • 免疫原：
    Recombinant Helicobacter pylori Vacuolating cytotoxin autotransporter protein (37-245AA)
  • 免疫原种属：
    Helicobacter pylori
  • 标记方式：
    Non-conjugated

    本页面中的产品，vacA Antibody (CSB-PA345927LA01B2M)，的标记方式是Non-conjugated。对于vacA Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA345927LB01B2M vacA Antibody, HRP conjugated ELISA
    FITC CSB-PA345927LC01B2M vacA Antibody, FITC conjugated
    Biotin CSB-PA345927LD01B2M vacA Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Induces vacuolation of eukaryotic cells. Causes ulceration and gastric lesions.
  • 基因功能参考文献：
    1. Helicobacter pylori VacA induces autophagic cell death in gastric epithelial cells via the endoplasmic reticulum stress pathway. PMID: 29238039
    2. The results indicate that cortactin is involved in the regulation of apoptosis induced by VacA in gastric cells. PMID: 26289258
    3. Genotype testing of vacA s- and m- region will be useful in screening susceptible individuals for duodenal ulcer development. PMID: 25063579
    4. These results suggested that cagA and vacA gene expression is upregulated in Helicobacter pylori, especially by host cell contact, and Fur has a role in the upregulation. PMID: 24020886
  • 亚细胞定位：
    [Vacuolating cytotoxin autotransporter]: Periplasm.; [Vacuolating cytotoxin]: Secreted. Cell surface.; [Vacuolating cytotoxin translocator]: Cell outer membrane; Multi-pass membrane protein.
  • 数据库链接：

    KEGG: hpy:HP0887

    STRING: 85962.HP0887