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vpx Antibody

  • 货号：
    CSB-PA356976LA01HLZ
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: vpx at 2.6μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 32 kDa
      Observed band size: 32 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Human immunodeficiency virus type 2 subtype A vpx Polyclonal antibody
  • Uniprot No.：
    P06939
  • 基因名：
    vpx
  • 别名：
    vpxProtein Vpx antibody; Viral protein X antibody; X ORF protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human immunodeficiency virus type 2 subtype A
  • 免疫原：
    Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx protein (1-112AA)
  • 免疫原种属：
    Human immunodeficiency virus type 2 subtype A
  • 标记方式：
    Non-conjugated

    本页面中的产品，vpx Antibody (CSB-PA356976LA01HLZ)，的标记方式是Non-conjugated。对于vpx Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA356976LB01HLZ vpx Antibody, HRP conjugated ELISA
    FITC CSB-PA356976LC01HLZ vpx Antibody, FITC conjugated
    Biotin CSB-PA356976LD01HLZ vpx Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription.
  • 亚细胞定位：
    Virion. Host nucleus. Note=Nuclear just after virion uncoating, or if expressed in the absence of unprocessed GAG.
  • 蛋白家族：
    Lentivirus VPX protein family