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  4. Recombinant Arabidopsis thaliana Calcineurin B-like protein 1 (CBL1)

Recombinant Arabidopsis thaliana Calcineurin B-like protein 1 (CBL1)

  • 中文名称：
    Recombinant Arabidopsis thaliana Calcineurin B-like protein 1(CBL1),Yeast
  • 货号：
    CSB-YP529313DOA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Calcineurin B-like protein 1(CBL1),Yeast
  • 货号：
    CSB-EP529313DOA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Calcineurin B-like protein 1(CBL1),Yeast
  • 货号：
    CSB-EP529313DOA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Calcineurin B-like protein 1(CBL1),Yeast
  • 货号：
    CSB-BP529313DOA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Calcineurin B-like protein 1(CBL1),Yeast
  • 货号：
    CSB-MP529313DOA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CBL1
  • Uniprot No.：
  • 别名：
    CBL1; SCABP5; At4g17615; dl4845w; FCAALL.122Calcineurin B-like protein 1; SOS3-like calcium-binding protein 5
  • 种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-213
  • 氨基酸序列
    GCFHSKAAK EFRGHEDPVK LASETAFSVS EVEALFELFK SISSSVVDDG LINKEEFQLA LFKSRKRENI FANRIFDMFD VKRKGVIDFG DFVRSLNVFH PNASLEDKID FTFRLYDMDC TGYIERQEVK QMLIALLCES EMKLADETIE IILDKTFEDA DVNQDGKIDK LEWSDFVNKN PSLLKIMTLP YLRDITTTFP SFVFHSEVDE IAT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a calcium sensor involved in the signaling pathway during growth and development and in response to abiotic stresses. May function as a positive regulator of salt and drought responses and as a negative regulator of cold response. Contributes to the regulation of early stress-related CBF/DREB transcription factors. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement. Involved in response to glucose and gibberellin during germination and seedling development and in response to cold stress. Involved in the calcium-dependent regulation by CIPK26 of reactive oxygen species production by the NADPH oxidase RBOHF.
  • 基因功能参考文献：
    1. These analyses reveal not only the fundamental role of CBL1 in the adjustment of central transcriptomic networks involved in maintaining adequate physiological homeostasis processes, but also that a high shoot-root dynamics is required for the proper deployment of Al resistance responses in the root. PMID: 28150888
    2. a crucial function for CBL1 and CBL9 in pollen germination and tube growth PMID: 23741064
    3. These results indicate a novel role for CBL1 in modulating responses to glucose and gibberellic acid signals. PMID: 23437128
    4. a novel general regulatory mechanism of CBL-CIPK complexes in that CBL phosphorylation at their flexible C terminus likely provokes conformational changes that enhance specificity and activity of CBL-CIPK complexes toward their target proteins PMID: 22253446
    5. Deletion of CBL1 may disturb the perception of calcium influx by cold stress and results in altered cold-induced signaling and adaption. PMID: 21600398
    6. The results of this study imply that plasma membrane-localized CBL1- and CBL9-CIPK23 complexes simultaneously regulate potassium transport processes in roots and in stomatal guard cells. PMID: 17922773
    7. Results show that a 12-amino acid peptide of CBL1 is sufficient to mediate dual lipid modification and to confer plasma membrane targeting. PMID: 18502848

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  • 亚细胞定位：
    Cell membrane; Lipid-anchor. Note=The cell membrane localization is S-acylation dependent and is abolished by 2-bromopalmitate (2-BP) treatment.
  • 蛋白家族：
    Calcineurin regulatory subunit family
  • 组织特异性：
    Preferentially expressed in stems, roots and siliques. Coexpressed with CIPK15/PKS3 in guard cells. Co-localized with CIPK23 in root tips and vascular bundles in the stem and the leaf, as well as in guard cells.
  • 数据库链接：

    KEGG: ath:AT4G17615

    STRING: 3702.AT4G17615.1

    UniGene: At.11088