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  4. Recombinant Arabidopsis thaliana Calcineurin B-like protein 4 (CBL4)

Recombinant Arabidopsis thaliana Calcineurin B-like protein 4 (CBL4)

  • 中文名称：
    Recombinant Arabidopsis thaliana Calcineurin B-like protein 4(CBL4),Yeast
  • 货号：
    CSB-YP530527DOA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Calcineurin B-like protein 4(CBL4),Yeast
  • 货号：
    CSB-EP530527DOA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Calcineurin B-like protein 4(CBL4),Yeast
  • 货号：
    CSB-EP530527DOA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Calcineurin B-like protein 4(CBL4),Yeast
  • 货号：
    CSB-BP530527DOA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Calcineurin B-like protein 4(CBL4),Yeast
  • 货号：
    CSB-MP530527DOA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CBL4
  • Uniprot No.：
  • 别名：
    CBL4; SOS3; At5g24270; MOP9.8Calcineurin B-like protein 4; Protein SALT OVERLY SENSITIVE 3
  • 种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-222
  • 氨基酸序列
    GCSVSKKKK KNAMRPPGYE DPELLASVTP FTVEEVEALY ELFKKLSSSI IDDGLIHKEE FQLALFRNRN RRNLFADRIF DVFDVKRNGV IEFGEFVRSL GVFHPSAPVH EKVKFAFKLY DLRQTGFIER EELKEMVVAL LHESELVLSE DMIEVMVDKA FVQADRKNDG KIDIDEWKDF VSLNPSLIKN MTLPYLKDIN RTFPSFVSSC EEEEMELQNV SS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a calcium sensor involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Binding of a CBL protein to the regulatory NAF domain of a CIPK serine-threonine protein kinase lead to the activation of the kinase in a calcium-dependent manner. Operates in synergy with CIPK24/SOS2 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. Involved in salt stress responses by mediating calcium-dependent microfilament reorganization. The CBL4/CIPK6 complex mediates translocation of AKT2 from the endoplasmic reticulum to the plasma membrane. Both myristoylation and S-acylation are required for AKT2 activation.
  • 基因功能参考文献：
    1. SOS3 mediated actin filament reorganization plays important roles in plant responses to salt stress. PMID: 23052592
    2. These data uncover a novel role of the SOS3 gene in modulation of lateral root developmental plasticity and adaptation in response to low salt stress. PMID: 21087263
    3. CBL4 is the barley homologue of the Arabidopsis SOS3 controlling the Na+ transport. PMID: 21047983
    4. purification and X ray structure PMID: 15213389
    5. calcium binding is responsible for the dimerization of SOS3 PMID: 15644219

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  • 亚细胞定位：
    Cell membrane; Lipid-anchor. Cytoplasm. Nucleus. Note=The cell membrane localization is S-acylation dependent.
  • 蛋白家族：
    Calcineurin regulatory subunit family
  • 数据库链接：

    KEGG: ath:AT5G24270

    STRING: 3702.AT5G24270.1

    UniGene: At.20610