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  4. Recombinant Arabidopsis thaliana E2F transcription factor-like E2FE (E2FE)

Recombinant Arabidopsis thaliana E2F transcription factor-like E2FE (E2FE)

  • 中文名称：
    拟南芥E2FE重组蛋白
  • 货号：
    CSB-YP839710DOA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    拟南芥E2FE重组蛋白
  • 货号：
    CSB-EP839710DOA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    拟南芥E2FE重组蛋白
  • 货号：
    CSB-EP839710DOA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    拟南芥E2FE重组蛋白
  • 货号：
    CSB-BP839710DOA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    拟南芥E2FE重组蛋白
  • 货号：
    CSB-MP839710DOA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    E2FE
  • Uniprot No.：
  • 别名：
    E2FE; DEL1; E2L3; ELP2; At3g48160; T24C20.40; E2F transcription factor-like E2FE; DP-E2F-like protein 1; E2F-like repressor E2L3
  • 种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-403
  • 氨基酸序列
    MSDLSPERFK LAVTSPSSIP ESSSALQLHH SYSRKQKSLG LLCTNFLALY NREGIEMVGL DDAASKLGVE RRRIYDIVNV LESVGVLTRR AKNQYTWKGF SAIPGALKEL QEEGVKDTFH RFYVNENVKG SDDEDDDEES SQPHSSSQTD SSKPGSLPQS SDPSKIDNRR EKSLGLLTQN FIKLFICSEA IRIISLDDAA KLLLGDAHNT SIMRTKVRRL YDIANVLSSM NLIEKTHTLD SRKPAFKWLG YNGEPTFTLS SDLLQLESRK RAFGTDITNV NVKRSKSSSS SQENATERRL KMKKHSTPES SYNKSFDVHE SRHGSRGGYH FGPFAPGTGT YPTAGLEDNS RRAFDVENLD SDYRPSYQNQ VLKDLFSHYM DAWKTWFSEV TQENPLPNTS QHR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication.
  • 基因功能参考文献：
    1. Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis PMID: 27505251
    2. involved in nematode feeding site generation PMID: 23518580
    3. Down-regulation and over-expression of CCS52 and DEL1 in Arabidopsis affected giant cell and syncytium growth, resulting in restrained nematode development, illustrating the need for mitotic activity and endo-reduplication for feeding site maturation. PMID: 22640471
    4. Overexpression of DEL1 does not completely abolish early endoreduplication on stress. PMID: 22535421
    5. The Arabidopsis (Arabidopsis thaliana) DEL1 gene was identified as a transcriptional target of the classical E2Fb and E2Fc transcription factors. PMID: 21908689
    6. DEL1 is a transcriptional repressor of the type-II cyclobutane pyrimidine dimer-photolyase DNA repair gene PHR1. PMID: 21131907
    7. DEL1 (EL3) is an important novel inhibitor of the endocycle and preserves the mitotic state of proliferating cells by suppressing transcription of genes that are required for cells to enter the DNA endoreduplication cycle. PMID: 15649366
    8. the atypical E2F transcription factor E2Fe/DEL1 controls the expression of the CDH1/FZR orthologous CCS52A2 gene from Arabidopsis thaliana PMID: 18787127

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    E2F/DP family
  • 组织特异性：
    Expressed exclusively in mitotically dividing cells. Highly expressed in young leaves and mature flowers. Lower expression in young stalk and in young and mature flowers.
  • 数据库链接：

    KEGG: ath:AT3G48160

    STRING: 3702.AT3G48160.2

    UniGene: At.35736