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  4. Recombinant Arabidopsis thaliana Heat stress transcription factor A-2 (HSFA2)

Recombinant Arabidopsis thaliana Heat stress transcription factor A-2 (HSFA2)

  • 中文名称：
    拟南芥HSFA2重组蛋白
  • 货号：
    CSB-YP528052DOA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    拟南芥HSFA2重组蛋白
  • 货号：
    CSB-EP528052DOA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    拟南芥HSFA2重组蛋白
  • 货号：
    CSB-EP528052DOA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    拟南芥HSFA2重组蛋白
  • 货号：
    CSB-BP528052DOA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    拟南芥HSFA2重组蛋白
  • 货号：
    CSB-MP528052DOA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    HSFA2
  • Uniprot No.：
  • 别名：
    HSFA2; HSF04; At2g26150; T19L18.4; Heat stress transcription factor A-2; AtHsfA2; AtHsf-04
  • 种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-345
  • 氨基酸序列
    MEELKVEMEE ETVTFTGSVA ASSSVGSSSS PRPMEGLNET GPPPFLTKTY EMVEDPATDT VVSWSNGRNS FVVWDSHKFS TTLLPRYFKH SNFSSFIRQL NTYGFRKIDP DRWEFANEGF LAGQKHLLKN IKRRRNMGLQ NVNQQGSGMS CVEVGQYGFD GEVERLKRDH GVLVAEVVRL RQQQHSSKSQ VAAMEQRLLV TEKRQQQMMT FLAKALNNPN FVQQFAVMSK EKKSLFGLDV GRKRRLTSTP SLGTMEENLL HDQEFDRMKD DMEMLFAAAI DDEANNSMPT KEEQCLEAMN VMMRDGNLEA ALDVKVEDLV GSPLDWDSQD LHDMVDQMGF LGSEP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress responses. Seems to be involved in other environmental stress responses. Activates ascorbate peroxidase 2 (APX2) in addition to several heat shock protein (HSPs).
  • 基因功能参考文献：
    1. Study demonstrated the flexible mode of heat response pathways involving bZIP28, HSFA2 and ROS-dependent signals. PMID: 28873003
    2. LIN treatment rapidly increases the levels of aggregated proteins in the chloroplast, unleashing a specific retrograde signaling pathway that up-regulates expression of ClpB3 and other nuclear genes encoding plastidial chaperones.Expression of HsfA2 and cpUPR-related target genes is independent of GUN1, a central integrator of retrograde signaling pathways PMID: 28937985
    3. transcriptional responses of the OPDA-responsive genes HsfA2 and DREB2A to the protein synthesis inhibitor cycloheximide and to the HSP90 inhibitor geldanamycin PMID: 25036962
    4. Self-regulation of HsfA2 expression is through a small truncated HsfA2 isoform encoded by the splice variant. PMID: 23503691
    5. Data indicate that cngc16 mutant pollen have attenuated expression of several heat-stress response genes, including two heat shock transcription factor genes, HsfA2 and HsfB1. PMID: 23370720
    6. We have established a previously unrecognized molecular connection between the downregulation of RPS1 expression in chloroplast and the activation of HsfA2-dependent heat-responsive genes in nucleus, which is required for heat tolerance in higher plants. PMID: 22570631
    7. These findings indicated that HsfA1d and HsfA1e not only regulate HsfA2 expression but also function as key regulators of the Hsf signaling network in response to environmental stress. PMID: 21471117
    8. The phenotype of seedlings overexpressing AtSUMO1 resembled the phenotype of AtHsfA2 knock out seedlings, which were more sensitive than wild type seedlings to repeated heat treatment. PMID: 20521085
    9. HsfA2 is an important transcription factor that confers anoxia tolerance to Arabidopsis seedlings. PMID: 20089772
    10. The accumulation of polyubiquitinated proteins causes the induction of HsfA2 expression under oxidative stress. PMID: 20147301
    11. AtHsfA2 has role in linking heat shock with oxidative stress signals in Arabidopsis PMID: 16483133
    12. The results of this study indicate that HsfA2 is a key regulator in the induction of the defence system under several types of environmental stress. PMID: 17059409
    13. HsfA2 functions as a heat-inducible transactivator, sustains the expression of Hsp genes, and extends the duration of acquired thermotolerance in Arabidopsis. PMID: 17085506
    14. HsfA2 protects plants against oxidative damage, organelle dysfunction, and subsequent cell death. PMID: 19342427
    15. HsfA2 appears to function not only in the triggering of response to environmental stress, but also in the amplification of the signal in the response. PMID: 19352026

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  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    HSF family, Class A subfamily
  • 数据库链接：

    KEGG: ath:AT2G26150

    STRING: 3702.AT2G26150.1

    UniGene: At.38933