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  4. Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase ATXR5 (ATXR5)

Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase ATXR5 (ATXR5)

  • 中文名称：
    Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase ATXR5(ATXR5),Yeast
  • 货号：
    CSB-YP851898DOA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase ATXR5(ATXR5),Yeast
  • 货号：
    CSB-EP851898DOA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase ATXR5(ATXR5),Yeast
  • 货号：
    CSB-EP851898DOA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase ATXR5(ATXR5),Yeast
  • 货号：
    CSB-BP851898DOA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase ATXR5(ATXR5),Yeast
  • 货号：
    CSB-MP851898DOA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ATXR5
  • Uniprot No.：
  • 别名：
    ATXR5; SDG15; SET15; At5g09790; 17I14.20; MTH16.26Histone-lysine N-methyltransferase ATXR5; EC 2.1.1.-; Protein SET DOMAIN GROUP 15; Trithorax-related protein 5; TRX-related protein 5
  • 种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-352
  • 氨基酸序列
    MATWNASSPA ASPCSSRRRT KAPARRPSSE SPPPRKMKSM AEIMAKSVPV VEQEEEEDED SYSNVTCEKC GSGEGDDELL LCDKCDRGFH MKCLRPIVVR VPIGTWLCVD CSDQRPVRKE TRKRRRSCSL TVKKRRRKLL PLVPSEDPDQ RLAQMGTLAS ALTALGIKYS DGLNYVPGMA PRSANQSKLE KGGMQVLCKE DLETLEQCQS MYRRGECPPL VVVFDPLEGY TVEADGPIKD LTFIAEYTGD VDYLKNREKD DCDSIMTLLL SEDPSKTLVI CPDKFGNISR FINGINNHNP VAKKKQNCKC VRYSINGECR VLLVATRDIS KGERLYYDYN GYEHEYPTHH FL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Histone methyltransferase that specifically monomethylates 'Lys-27' of histone H3 (H3K27me1). Has much higher activity on nucleosomes containing H3.1 than H3.3. Involved in the formation of constitutive heterochromatin and the silencing of heterochromatic elements. Influences which sets of rRNA gene variants are expressed or silenced.
  • 基因功能参考文献：
    1. Several molecular determinants regulate ATXR5/6 methyltransferase activity and epigenetic inheritance of H3.1 K27me1 mark in plants. PMID: 28383693
    2. this study identifies a histone-modifying enzyme ATXR5 that selectively methylates the replication-dependent histone H3 variant H3.1. PMID: 24626927
    3. mutations in the homologous histone 3 lysine 27 (H3K27) monomethyltransferases, ARABIDOPSIS TRITHORAX-RELATED PROTEIN5 (ATXR5) and ATXR6, lead to re-replication of specific genomic locations PMID: 20631708
    4. ATXR5 and ARXR6 interact with proliferating cell nuclear antigen (PCNA) and are associated with a role in the cell cycle or DNA replication. [ATXR5] PMID: 16771839
    5. These results indicate that ATXR5 and ATXR6 form a new class of H3K27 methyltransferases and that H3K27me1 represents a previously uncharacterized pathway required for transcriptional repression in Arabidopsis. PMID: 19503079

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  • 亚细胞定位：
    Nucleus. Plastid, chloroplast. Note=Never found in plastids and the nucleus within the same cell.
  • 蛋白家族：
    Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, TRX/MLL subfamily
  • 组织特异性：
    Expressed in leaves, roots, stems, flowers, siliques and developing pollen. Up-regulated in tissues where cell division is active.
  • 数据库链接：

    KEGG: ath:AT5G09790

    STRING: 3702.AT5G09790.2

    UniGene: At.27076