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  4. Recombinant Arabidopsis thaliana Serine/threonine-protein kinase Aurora-3 (AUR3)

Recombinant Arabidopsis thaliana Serine/threonine-protein kinase Aurora-3 (AUR3)

  • 中文名称：
    Recombinant Arabidopsis thaliana Serine/threonine-protein kinase Aurora-3(AUR3),Yeast
  • 货号：
    CSB-YP528946DOA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Serine/threonine-protein kinase Aurora-3(AUR3),Yeast
  • 货号：
    CSB-EP528946DOA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Serine/threonine-protein kinase Aurora-3(AUR3),Yeast
  • 货号：
    CSB-EP528946DOA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Serine/threonine-protein kinase Aurora-3(AUR3),Yeast
  • 货号：
    CSB-BP528946DOA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Serine/threonine-protein kinase Aurora-3(AUR3),Yeast
  • 货号：
    CSB-MP528946DOA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    AUR3
  • Uniprot No.：
  • 别名：
    AUR3; At2g45490; F17K2.2Serine/threonine-protein kinase Aurora-3; AtAur3; EC 2.7.11.1; Aurora-like kinase 3
  • 种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-288
  • 氨基酸序列
    MSKKSTESDA GNTEKQWSLA DFEIGRPLGK GKFGRVYLAR EAKSKYIVAL KVIFKEQIEK YKIHHQLRRE MEIQTSLRHP NILRLFGWFH DNERIFLILE YAHGGELYGV LKQNGHLTEQ QAATYIASLS QALAYCHGKC VIHRDIKPEN LLLDHEGRLK IADFGWSVQS SNKRKTMCGT LDYLAPEMVE NRDHDYAVDN WTLGILCYEF LYGNPPFEAE SQKDTFKRIL KIDLSFPLTP NVSEEAKNLI SQLLVKDPSK RLSIEKIMQH PWIVKNADPK GVCASIDI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Phosphorylates in vitro histone H3 at 'Ser-10' (H3S10ph) and 'Ser-28' (H3S28ph), but not at 'Thr-3' (H3T3ph) or 'Thr-11' (H3T11ph). Colocalizes with phosphorylated histone H3 during mitosis. Associates with cytoskeletal structures that are necessary for cytokinesis and with the microtubule spindle.
  • 基因功能参考文献：
    1. AtAUR1 and AtAUR3 have both redundant and distinct functions through interactions with transcription factors (TFs). In addition, database analysis revealed that most of the highly AtAUR-interacting TFs contained a detectable phosphopeptide that was consistent with the consensus motifs for human AURs, suggesting that these TFs are substrates of the AtAURs. PMID: 27734173
    2. Aurora kinase AtAUR3 showed dot-like distribution on condensed chromosomes at prophase and then localized at the metaphase plate, and overexpression of AtAUR3 induces disassembly of spindle microtubules and alteration of orientation of cell division. PMID: 16028112
  • 亚细胞定位：
    Cytoplasm, perinuclear region. Nucleus. Chromosome. Chromosome, centromere.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily
  • 组织特异性：
    Abundant in roots, flowers and flower buds, low or absent in expanded leaves, stems and siliques.
  • 数据库链接：

    KEGG: ath:AT2G45490

    STRING: 3702.AT2G45490.1

    UniGene: At.37011