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  4. Recombinant Borrelia burgdorferi Telomere resolvase resT (resT)

Recombinant Borrelia burgdorferi Telomere resolvase resT (resT)

  • 货号：
    CSB-YP527441BUD
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP527441BUD
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP527441BUD-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP527441BUD
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP527441BUD
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    resT; BB_B03; Telomere resolvase ResT; EC 3.1.22.-
  • 种属：
    Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-449
  • 氨基酸序列
    MPPKVKIKND FEIFRKELEI LYKKYLNNEL SYLKLKEKLK ILAENHKAIL FRKDKFTNRS IILNLSKTRK IIKEYINLSV IERIRRDNTF LFFWKSRRIK ELKNIGIKDR KKIEELIFSN QMNDEKSYFQ YFIDLFVTPK WLNDYAHKYK IEKINSYRKE QIFVKINLNT YIEIIKLLLN QSRDIRLKFY GVLMAIGRRP VEVMKLSQFY IADKNHIRME FIAKKRENNI VNEVVFPVFA DPELIINSIK EIRYMEQTEN LTKEIISSNL AYSYNRLFRQ IFNNIFAPEE SVYFCRAIYC KFSYLAFAPK NMEMNYWITK VLGHEPNDIT TAFHYNRYVL DNLDDKADNS LLTLLNQRIY TYVRRKATYS TLTMDRLESL IKEHHIFDDN YIKTLIVIKN LMLKDNLETL AMVRGLNVKI RKAFKATYGY NYNYIKLTEY LSIIFNYKL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the conservative, sequence-specific DNA breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Breaks two phosphodiester bonds in a single DNA duplex and joins each end with the opposite DNA strand to form covalently closed hairpin telomeres.
  • 基因功能参考文献：
    1. ResT possesses DNA-dependent ATPase activity that promotes DNA unwinding with a 3-5 polarity. ResT can unwind a variety of substrates including synthetic replication forks and D-loops. We demonstrate that ResT's twin activities of DNA unwinding and annealing can drive regression of a model replication fork. PMID: 28180323
  • 亚细胞定位：
    Chromosome, telomere.
  • 数据库链接：

    KEGG: bbu:BB_B03