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  4. Recombinant Bovine Carboxypeptidase B2 (CPB2)

Recombinant Bovine Carboxypeptidase B2 (CPB2)

  • 货号：
    CSB-YP642528BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP642528BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP642528BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP642528BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP642528BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    CPB2Carboxypeptidase B2; EC 3.4.17.20; Carboxypeptidase U; CPU; Plasma carboxypeptidase B; pCPB; Thrombin-activable fibrinolysis inhibitor; TAFI
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    115-423
  • 氨基酸序列
    ASSSYY EQYHSLNEIY SWIEVMTERY PDMVEKIHIG SSYEKYPLYV LKVSKKEQRA KNAMWIDCGI HAREWISPAF CLWFVGSVTY YYGKEKMHTN LLKHMDFYIM PVVNVDGYDY TWKKDRMWRK NRSLHEKNAC VGTDLNRNFA SKHWCGEGAS SSSCSEIYCG TYPESEPEVK AVADFLRRNI KHIKAYISMH SYSQKIVFPY SYSRSRSKDH EELSLVAREA VFAMENIHRN IRYTHGSGSE SLYLAPGGSD DWIYDLGIKY SFTFELRDKG KYGFLLPESY IRPTCSEALV AVAKIASHVV KNV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.
  • 基因功能参考文献：
    1. analysis of the crystal structure of thrombin-activable fibrinolysis inhibitor (TAFI) and description of the structural basis for its intrinsic activity and the short half-life of TAFIa PMID: 18669641
    2. Purified bovine TAFI activated in the presence of a proteinaceous inhibitor renders a stable enzyme-inhibitor complex. PMID: 18722183
    3. Findings presented here suggest that the properties of these two orthologous proteins are similar and that conclusions reached using the bovine TAFI may be extrapolated to the human TAFI protein. PMID: 19416536
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Peptidase M14 family
  • 数据库链接：

    KEGG: bta:508222

    STRING: 9913.ENSBTAP00000009300

    UniGene: Bt.93764