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  4. Recombinant Bovine DNA repair protein XRCC3 (XRCC3)

Recombinant Bovine DNA repair protein XRCC3 (XRCC3)

  • 货号：
    CSB-YP600185BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP600185BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP600185BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP600185BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP600185BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    XRCC3
  • Uniprot No.：
  • 别名：
    XRCC3; DNA repair protein XRCC3; X-ray repair cross-complementing protein 3
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-341
  • 氨基酸序列
    MDLDRLDLNP RIVAAVKKAK LRSVKEVLHL SGPDLQRRTH LSSPDVQLLL RASASLLRGH GVCTALHLLR QEGPFPEQHQ RLSLGCPVLD ALLRGGLPLD GITELAGRSS AGKTQLALQL CLAVQLPPRH GGLGAGAVYV CTEDAFPSRR LQQLIAQQQR LRADVPGHVI SKIRFGHQIF IEHAADVDTL LQCVREKVPV LLARGMARLV VIDSVAAPFR CEFDGAALAL RAQRLLALGA ELRRLSCAFR SPVLCVNQVT EAVEEQDLVA GPPGMSPALG ITWANQLLVR LLADRQRPEE APLTPPGRTL RVVFAPHLPA SSCSYTIAAE GVRGMPGTAC S
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the RAD21 paralog protein complex CX3 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, CX3 acts downstream of RAD51 recruitment; the complex binds predominantly to the intersection of the four duplex arms of the Holliday junction (HJ) and to junctions of replication forks. Involved in HJ resolution and thus in processing HR intermediates late in the DNA repair process; the function may be linked to the CX3 complex and seems to involve GEN1 during mitotic cell cycle progression. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C.
  • 亚细胞定位：
    Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion matrix.
  • 蛋白家族：
    RecA family, RAD51 subfamily
  • 数据库链接：

    KEGG: bta:768244

    STRING: 9913.ENSBTAP00000013145

    UniGene: Bt.41484