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  4. Recombinant Bovine Ectodysplasin-A (EDA), partial

Recombinant Bovine Ectodysplasin-A (EDA), partial

  • 中文名称：
    牛EDA重组蛋白
  • 货号：
    CSB-YP857727BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    牛EDA重组蛋白
  • 货号：
    CSB-EP857727BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    牛EDA重组蛋白
  • 货号：
    CSB-EP857727BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    牛EDA重组蛋白
  • 货号：
    CSB-BP857727BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    牛EDA重组蛋白
  • 货号：
    CSB-MP857727BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    EDA
  • Uniprot No.：
  • 别名：
    EDA; ED1Ectodysplasin-A; Ectodermal dysplasia protein; Ectodysplasin-1) [Cleaved into: Ectodysplasin-A; membrane form; Ectodysplasin-A; secreted form]
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R. Isoform A1 binds only to the receptor EDAR, while isoform A2 binds exclusively to the receptor EDA2R. May also play a role in cell adhesion.; Isoform A1 binds only to the receptor EDAR, while isoform A2 binds exclusively to the receptor EDA2R.; Isoform A2 binds exclusively to the receptor EDA2R.
  • 基因功能参考文献：
    1. s identifya mutation, never described before, that changes the regulation of alternative splicing in the EDA gene and causes ectodermal dysplasia in cattle. PMID: 21740563
    2. The 161-bp-long LINE1-derived-pseudoexon introduces a shift in reading frame and a premature stop codon early in EDA exon 2 and is probably the cause of XHED in this Danish Red Holstein family. PMID: 22034998
    3. describe a novel mutation of the EDA gene in which a 19 bp deletion in exon 1 in male Holstein calves demonstrated the phenotypic features of EDA PMID: 21410470
    4. A single point mutation within this gene disrupts correct splicing at two different splice sites and leads to anhidrotic ectodermal dysplasia in cattle PMID: 12021844
  • 亚细胞定位：
    Cell membrane; Single-pass type II membrane protein.; [Ectodysplasin-A, secreted form]: Secreted.
  • 蛋白家族：
    Tumor necrosis factor family
  • 数据库链接：

    KEGG: bta:616179

    STRING: 9913.ENSBTAP00000016649

    UniGene: Bt.101611