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  4. Recombinant Bovine Pentraxin-related protein PTX3 (PTX3)

Recombinant Bovine Pentraxin-related protein PTX3 (PTX3)

  • 中文名称：
    牛PTX3重组蛋白
  • 货号：
    CSB-MP610820BO
  • 规格：
    ￥2640
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    PTX3
  • Uniprot No.：
  • 别名：
    PTX3; Pentraxin-related protein PTX3; Pentaxin-related protein PTX3
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full Length of Mature Protein
  • 来源：
    Mammalian cell
  • 分子量：
    44.7 kDa
  • 表达区域：
    18-382aa
  • 氨基酸序列
    ENSDDYELMYVNLDNEIDNGLHPTEDPTPCDCSRENSEWDKLFTMLENSQMREGMLLQATDVMLRGELQKLQAELGRLEGSLQKLCGPEAPSETRLARALDDLLQASRDAGRRLARLEDAGALRPQEEAGRALGAVLEELRRTRADLRAVQGWAASRWLPAGCETAILFPMRSKKIFASVHPVTPMKLETFSACIWVKATEVLNKTVLFSYGTKRNPYEIQLYLSYRSIMLVVGGEENRLVADAVISLGTWTHLCSTWDSKKGHMALWVNGDSVATAVDMATGHVVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWEGVLSNEEIREAGGAESCHIRGNVVGWGVTEIQPHGGAQYVY
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal Flag-Myc-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 产品描述：

    Recombinant Bovine PTX3 protein is a mammalian cell-expressed protein (Full Length of Mature Protein). Molecularly, this PTX3 protein is characterized by N-terminal Flag-Myc tag, and an internal Bovine PTX3 DNA fragment, 18-382aa. Its purity is 90%+ measured by SDS-PAGE. This recombinant production is the biotechnological process of generating a specific protein, and the host cell that we use are HEK293 cells. The Mammalian cell expression system can provide the most complete glycosylation, such as the complex N-type glycosylation and accurate O-glycosylation modifications, usually, the protein expressed by the mammalian cell system is closest to the conformation of the natural protein.

    PTX3 is a protein coding gene that encodes Pentraxin-related protein PTX3. According to some research, PTX3 may have the following features.
    The long pentraxin Ptx3 is a secreted pattern recognition receptor with a non-redundant role in resistance to selected microbial agents. PTX3 is a useful new serological marker that rapidly reflects tissue inflammation and damage in different clinical conditions. PTX3 binds to P-selectin and attenuates neutrophil recruitment to sites of inflammation. The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localized in extracellular traps. PTX3 is an extrinsic tumor suppressor that regulates complement-dependent inflammation in cancer.

  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.
  • 基因功能参考文献：
    1. there is an FGF2-binding domain in the N-terminal extension of PTX3 spanning the PTX3-(97-110) region PMID: 16769728
  • 亚细胞定位：
    Secreted.
  • 数据库链接：

    KEGG: bta:541148

    STRING: 9913.ENSBTAP00000011863

    UniGene: Bt.7541