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  4. Recombinant Bovine Plasma serine protease inhibitor (SERPINA5)

Recombinant Bovine Plasma serine protease inhibitor (SERPINA5)

  • 中文名称：
    牛SERPINA5重组蛋白
  • 货号：
    CSB-YP868236BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    牛SERPINA5重组蛋白
  • 货号：
    CSB-EP868236BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    牛SERPINA5重组蛋白
  • 货号：
    CSB-EP868236BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    牛SERPINA5重组蛋白
  • 货号：
    CSB-BP868236BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    牛SERPINA5重组蛋白
  • 货号：
    CSB-MP868236BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    SERPINA5; Plasma serine protease inhibitor; Protein C inhibitor; PCI; Serpin A5
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    25-404
  • 氨基酸序列
    KKIQEV PPAVTTAPPG SRDFVFDLYR ALAAAAPAQN IFFSPLSITV SLAMLSLGAQ SNTKAQILEG LGIGPGEGSE EELHSASQRL LRELQQPQDS LQLSLGNALF TKPRLPIQEA FLGAMRTLYL ADTFPTNFED PEGAKKKIND YVAKQTKGKI VDLIKSLDGT QVMVMVNYIF FKAKWETSFN LKSTHEQDFY VTPETVVRVP MMKQQDQFYY LLDRNLSCKV VGVPYQGNAT AFFILPREGE MEQVENGLKE KTLKKWLRMP MKRRLELYLP KFSIEGSYQL EEVLPKLGIR DIFTSDADLT GISNHSSIRV SEMVHKAVVE VDESGTQAAA ATGMVITFKS ARLGSQRIVF NRPFLVLIVK NSKHILFLGK VTRP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin complex. Acts as an anticoagulant factor by inhibiting blood coagulation factors like prothrombin, factor XI, factor Xa, plasma kallikrein and fibrinolytic enzymes such as tissue- and urinary-type plasminogen activators. In seminal plasma, inactivates several serine proteases implicated in the reproductive system. Inhibits the serpin acrosin; indirectly protects component of the male genital tract from being degraded by excessive released acrosin. Inhibits tissue- and urinary-type plasminogen activator, prostate-specific antigen and kallikrein activities; has a control on the sperm motility and fertilization. Inhibits the activated protein C-catalyzed degradation of SEMG1 and SEMG2; regulates the degradation of semenogelin during the process of transfer of spermatozoa from the male reproductive tract into the female tract. In urine, inhibits urinary-type plasminogen activator and kallikrein activities. Inactivates membrane-anchored serine proteases activities such as MPRSS7 and TMPRSS11E. Inhibits urinary-type plasminogen activator-dependent tumor cell invasion and metastasis. May also play a non-inhibitory role in seminal plasma and urine as a hydrophobic hormone carrier by its binding to retinoic acid.
  • 亚细胞定位：
    Secreted, extracellular space.
  • 蛋白家族：
    Serpin family
  • 组织特异性：
    Expressed strongly in the liver, and moderately in the kidney and testis, but not in other tissues tested.
  • 数据库链接：

    KEGG: bta:338050

    STRING: 9913.ENSBTAP00000005307

    UniGene: Bt.2712