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  4. Recombinant Bovine Ras GTPase-activating protein-binding protein 1 (G3BP)

Recombinant Bovine Ras GTPase-activating protein-binding protein 1 (G3BP)

  • 货号：
    CSB-YP654171BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP654171BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP654171BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP654171BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP654171BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    G3BP1; G3BPRas GTPase-activating protein-binding protein 1; G3BP-1; EC 3.6.4.12; EC 3.6.4.13; ATP-dependent DNA/RNA helicase G3BP
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-465
  • 氨基酸序列
    VMEKPSPLL VGREFVRQYY TLLNQAPDML HRFYGKNSSY VHGGLDSNGK PADAVYGQKE IHRKVMSQNF TNCHTKIRHV DAHATLNDGV VVQVMGLLSN NNQALRRFMQ TFVLAPEGSV ANKFYVHNDI FRYQDEVFGG FITEPQEESE EEVEEPEERQ QTPEVVPDDS GTFYDQTVSN DLEEHLEEPV AEPEPEPEPE PEQEPVSEVQ EEKSEPVLEE TAPEDVQKSS SPAPADIAQT VQEDLRTFSW ASVTSKNLPP SGAVPVTGIP PHVVKVPASQ PRPESKPESQ IPLQRPQRDQ RVREQRINVP PQRGPRPVRE AGEQGDVEPR RIVRHPDSHQ LFIGNLPHEV DKSELKDFFQ NYGNVVELRI NSGGKLPNFG FVVFDDSEPV QKVLSNRPIM FRGEVRLNVE EKKTRAAREG DRRDNRLRGP GGPRGGLGGG MRGPPRGGMV QKPGFGVGRS IAPRQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR.
  • 亚细胞定位：
    Cytoplasm, cytosol. Perikaryon. Cytoplasm, Stress granule. Nucleus.
  • 数据库链接：

    KEGG: bta:534214

    STRING: 9913.ENSBTAP00000027067

    UniGene: Bt.5197