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  4. Recombinant Bovine Urea transporter 1 (SLC14A1), partial

Recombinant Bovine Urea transporter 1 (SLC14A1), partial

  • 中文名称：
    牛SLC14A1重组蛋白
  • 货号：
    CSB-YP712737BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    牛SLC14A1重组蛋白
  • 货号：
    CSB-EP712737BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    牛SLC14A1重组蛋白
  • 货号：
    CSB-EP712737BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    牛SLC14A1重组蛋白
  • 货号：
    CSB-BP712737BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    牛SLC14A1重组蛋白
  • 货号：
    CSB-MP712737BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SLC14A1
  • Uniprot No.：
  • 别名：
    SLC14A1; UT-B; Urea transporter 1; Solute carrier family 14 member 1; Urea transporter B; UT-B; Urea transporter; erythrocyte
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.
  • 基因功能参考文献：
    1. Data suggest that expression of UT-B (urea transporter B) in rumen mucosa can be modulated by dietary factors; here, UT-B and AQP3 (aquaglyceroporin-3) expression are upregulated with solid food intake (low-protein diet of plant forage) at weaning. PMID: 24812069
    2. the rate of urea conduction in UT-B is increased by hypoosmotic stress, and the site of osmoregulation coincides with the location of the energy barrier PMID: 22733730
    3. Bovine UT-B is expressed in bovine rumen and may function to transport urea into rumen as part of ruminant urea nitrogen salvaging process. PMID: 15845882
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Restricted to the basolateral membrane in various portions of the urothelium.
  • 蛋白家族：
    Urea transporter family
  • 组织特异性：
    Isoform 1 and isoform 2 are expressed in kidney. Also expressed in the rumen (at protein level). Isoform 2 seems predominant in both tissues.
  • 数据库链接：

    KEGG: bta:493988

    STRING: 9913.ENSBTAP00000044109

    UniGene: Bt.66422