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Recombinant Chicken Calbindin (CALB1)

  • 中文名称：
    Recombinant Chicken Calbindin(CALB1),Yeast
  • 货号：
    CSB-YP004432CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Chicken Calbindin(CALB1),Yeast
  • 货号：
    CSB-EP004432CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Chicken Calbindin(CALB1),Yeast
  • 货号：
    CSB-EP004432CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Chicken Calbindin(CALB1),Yeast
  • 货号：
    CSB-BP004432CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Chicken Calbindin(CALB1),Yeast
  • 货号：
    CSB-MP004432CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    CALB1Calbindin; Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein; avian-type
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-262
  • 氨基酸序列
    TAETHLQGV EISAAQFFEI WHHYDSDGNG YMDGKELQNF IQELQQARKK AGLDLTPEMK AFVDQYGKAT DGKIGIVELA QVLPTEENFL LFFRCQQLKS SEDFMQTWRK YDSDHSGFID SEELKSFLKD LLQKANKQIE DSKLTEYTEI MLRMFDANND GKLELTELAR LLPVQENFLI KFQGVKMCAK EFNKAFEMYD QDGNGYIDEN ELDALLKDLC EKNKKELDIN NLATYKKSIM ALSDGGKLYR AELALILCAE EN
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
  • 基因功能参考文献：
    1. The vector-based transient receptor potential vanilloid 6(TRPV6)-shRNA can efficiently suppress the mRNA and protein expression of TRPV6 in chicken osteoblasts, and TRPV6 regulates the expression of calbindin-D28K during Ca2+ transport. PMID: 25681476
    2. increase of transient receptor potential cation channel subfamily V member 6 (TRPV6) and calbindin-D28k expression during eggshell formation suggests that active Calcium(2+) transport exerts effects in delivering active calcium in egg shell gland PMID: 23796121
    3. Calbindin-D28k has significant roles in neuroplasticity of the retina during postnatal development, when it is stimulated with different light conditions. PMID: 23447106
    4. This study concluded that calbindin-D28k localization in intestinal segments and eggshell gland is negatively affected by high ambient temperature which might be related to the deterioration of eggshell quality characteristics under heat stress. PMID: 22912464
    5. detailed characterization of the Ca2+-binding and oligomerization properties of each individual EF-hand peptide using CD spectroscopy and analytical ultracentrifugation PMID: 16216075
    6. expression of Ca-D28K in 25 sporadic cases of chicken nephroblastomas PMID: 16617996
    7. Calbindin showed a specific spatiotemporal expression pattern and was expressed in a region (area)-specific but dynamic manner during development of the hippocampus and hyperpallium. PMID: 16786551
    8. There may be a close correlation between the alpha2 subunit and calbindin in chicken nociceptive spinal neurons. PMID: 17822792
    9. Auditory-stimulated chick embryos showed a significant increase in the proportion of immunopositive neurons and the levels of expression of calbindin D-28K compared to the control at all developmental stages studied. PMID: 18096144

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  • 蛋白家族：
    Calbindin family
  • 组织特异性：
    Highly abundant in supporting cells. Also present in hair cells.
  • 数据库链接：

    KEGG: gga:396519

    STRING: 9031.ENSGALP00000026395

    UniGene: Gga.3286