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  4. Recombinant Chicken Homeobox protein DLX-5 (DLX5)

Recombinant Chicken Homeobox protein DLX-5 (DLX5)

  • 货号：
    CSB-YP006956CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP006956CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP006956CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP006956CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP006956CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    DLX5; DLX-5Homeobox protein DLX-5; cDlx
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-286
  • 氨基酸序列
    MTAVFDRRVP GIRSSDFQPP FQSAAAMHHP SQESPTLPES SATDSDYYSP TGAAPHGYCS PTSASYGKAL NPYQYQYGMN GSAGTYPAKA YADYGYGSPY HQYGGAYGRG QSSAGQPEKE VAEPEVRMVN GKPKKVRKPR TIYSSFQLAA LQRRFQKTQY LALPERAELA ASLGLTQTQV KIWFQNKRSK IKKIMKNGEM PPEHSPSSSD PMACNSPQSP AVWEPQGSSR SLGHHGHGHP PAANPSPGSY LESPSAWYPA ASPLGSHLQP HGSLQHPLAL PSGTIY
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional factor involved in bone development. Could be involved in apical ectodermal ridge activity, pattern formation, and cartilage differentiation. Binds to DNA.
  • 基因功能参考文献：
    1. We find Dlx5 and Dlx6 to be quantitatively indistinguishable on a variety of natural cis-regulatory sequences in a heterologous cellular context but observed quantitatively different transcriptional outputs in cells that normally express these genes, suggesting differential interactions with co-evolved co-activators. PMID: 27416760
    2. Inner ear expression patterns of Dlx3, Dlx5, and Dlx6 were examined during the first 7 days of chicken embryonic development. PMID: 15672396
    3. ectethmoid formation depends upon Dlx5 and Dlx6 expression in a restricted ectodermal territory of the anterior neural folds PMID: 21270050
    4. Dlx5 has roles during multiple stages of chondrocyte differentiation and is a general regulator of differentiation in the skeleton PMID: 12895028
    5. investigated the domain requirements and transcriptional activities associated with Dlx5- and Dlx6-mediated chondrogenesis PMID: 17027239
    6. Dlx5 and 6 genes may be involved in specification of the elbow joint and/or in providing positional information that specifies the site at which the elbow joint will form PMID: 17051482
    7. Dlx5 and related Dlx factors play a pivotal role in the onset of differentiation of chick calvaria osteoblasts. PMID: 17335796

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Distal-less homeobox family
  • 数据库链接：

    KEGG: gga:373969

    STRING: 9031.ENSGALP00000015233

    UniGene: Gga.919