Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Chicken Osteopontin (SPP1)

Recombinant Chicken Osteopontin (SPP1)

  • 货号：
    CSB-YP022603CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP022603CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP022603CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP022603CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP022603CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    SPP1; Osteopontin; Bone sialoprotein 1; Secreted phosphoprotein 1; SPP-1
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    17-264
  • 氨基酸序列
    WPVS KSRQHAISAS SEEKYDPRSH HTHRYHQDHV DSQSQEHLQQ TQNDLASLQQ THYSSEENAD VPEQPDFPDI PSKSQEAVDD DDDDDNDSND TDESDEVVTD FPTEAPVTPF NRGDNAGRGD SVAYGFRAKA HVVKASKLRK AARKLIEDDA TAEVGDSQLA GLWLPKESRE QDSRELAQHQ SVENDSRPRF DSPEVGGGDS KASAGVDSRE SLASRSAVDT SNQTLESAED AEDRHSIENN EVTR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Major non-collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.; Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
  • 基因功能参考文献：
    1. results of this study indicate that SPP1 is novel in that its expression is down-regulated by estrogen in epithelial cells of the chicken oviduct and that it is up-regulated in chicken ovarian endometrioid tumor that could be used for monitoring effects of therapies for this disease in laying hens. PMID: 22588173
    2. fibroblast growth factor signaling directly activates osteopontin expression independent of chondrocytes differentiation PMID: 16253490
    3. Polymorphisms within the osteopontin gene (SPP1) are associated with 5-week body weight. PMID: 16734694
    4. OPN inhibited calcite growth in vitro at the crystallographic faces producing altered crystal morphology and circular growth step topography PMID: 18511297
    5. Matrix-mineral relationships in the eggshell at the ultrastructural level were studied using scanning and transmission electron microscopy, and the distribution of osteopontin is described. PMID: 18698131
    6. The effects of osteopontin and calbindin synthesis in the eggshell gland on the quality of egg shells in laying hens are reported. PMID: 19211537

    显示更多

    收起更多

  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Osteopontin family
  • 数据库链接：

    KEGG: gga:395210

    STRING: 9031.ENSGALP00000017754

    UniGene: Gga.3551