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  4. Recombinant Chicken Protein NOV (NOV)

Recombinant Chicken Protein NOV (NOV)

  • 中文名称：
    鸡NOV重组蛋白
  • 货号：
    CSB-YP015956CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡NOV重组蛋白
  • 货号：
    CSB-EP015956CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡NOV重组蛋白
  • 货号：
    CSB-EP015956CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡NOV重组蛋白
  • 货号：
    CSB-BP015956CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡NOV重组蛋白
  • 货号：
    CSB-MP015956CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NOV
  • Uniprot No.：
  • 别名：
    CCN3; NOV; CCN family member 3; Cellular communication network factor 3; Nephroblastoma-overexpressed gene protein; Protein NOV
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    25-351
  • 氨基酸序列
    SGREAA CPRPCGGRCP AEPPRCAPGV PAVLDGCGCC LVCARQRGES CSPLLPCDES GGLYCDRGPE DGGGAGICMV LEGDNCVFDG MIYRNGETFQ PSCKYQCTCR DGQIGCLPRC NLGLLLPGPD CPFPRKIEVP GECCEKWVCD PRDEVLLGGF AMAAYRQEAT LGIDVSDSSA NCIEQTTEWS ACSKSCGMGF STRVTNRNQQ CEMVKQTRLC MMRPCENEEP SDKKGKKCIQ TKKSMKAVRF EYKNCTSVQT YKPRYCGLCN DGRCCTPHNT KTIQVEFRCP QGKFLKKPMM LINTCVCHGN CPQSNNAFFQ PLDPMSSEAK I
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Immediate-early protein likely to play a role in cell growth regulation. Its overexpression is associated with tumorigenesis and expression of a N-terminal-truncated version of CCN3 gene in chicken embryonic fibroblasts (CEF) is sufficient to induce the transformation of CEF in vitro.
  • 基因功能参考文献：
    1. The expression of NOV was intense in the developing tendons and in the developing joints, whereas the chondrogenic blastemas were negative for NOV transcripts. NOV induced intense upregulation of Tenascin C and, at a reduced level, of alpha 5 Integrin, Sox9, and Activin beta-A. PMID: 21931747
    2. Results establish the expression pattern of CCN3 in the developing retina, and show CCN3 expression is induced by activated BMP signaling, whereas Notch signaling decreases CCN3 mRNA and protein levels in Muller cells and has no effect in retinal neurons. PMID: 22038708
  • 亚细胞定位：
    Secreted. Cytoplasm. Cell junction, gap junction.
  • 蛋白家族：
    CCN family
  • 组织特异性：
    Brain and heart, and at a lower level in muscle and intestine, in the embryo. Lung and less so in brain and spleen, in adult chicken.
  • 数据库链接：

    KEGG: gga:396204

    STRING: 9031.ENSGALP00000025912

    UniGene: Gga.2587