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  4. Recombinant Chicken Tsukushin (TSKU)

Recombinant Chicken Tsukushin (TSKU)

  • 货号：
    CSB-YP025140CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP025140CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP025140CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP025140CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP025140CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TSKU
  • Uniprot No.：
  • 别名：
    TSKU; LRRC54; TSK; Tsukushin; Tsukushi; C-TSK; Leucine-rich repeat-containing protein 54
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    20-369
  • 氨基酸序列
    K TCFPGCHCEV ESFGLFDSFS LTKVDCSGIG SHIVPVPIPL DTSYLDLSSN KLETINESML TGPGYTTLVS LDLSYNNIAK ISSTTFSRLR YLESLDLSHN SLEVLPEDCF SSSPLGDIDL SNNKLLDIAL DVFASKGQGK PLNVDLSNNM LSKITRNHEK SIPNIQNLNL SGNRLTSVPN LQGIPLRYLN LDGNPLAKIE KGDFKGLKGL IHLSLSGLHD FRELSPYSFK ELPALQVLDL SNNPNLRSLT AEVIFGLNSI QELNLSGTGV SSLPKTVLKY LPSLKSITLR KNIQCFKTIK EGQYHRQIGL TKLGLGAEEL LWCKTPCPRP VCRCRDKPLQ SAPQNLPTP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Contributes to various developmental events through its interactions with multiple signaling pathways. Dorsalizing factor involved in the induction of Hensen's node by inhibiting bone morphogenetic proteins during gastrulation and by enhancing DVR1/VG1 activity. Wnt signaling inhibitor which competes with WNT2B for binding to Wnt receptor FZD4 and represses WNT2B-dependent development of the peripheral eye.; Shows strong bone morphogenetic protein antagonistic activity.; Shows weak bone morphogenetic protein antagonistic activity.
  • 基因功能参考文献：
    1. TSK isoforms play a crucial role in chick axis formation by locally modulating VG1 and BMP activities during gastrulation. PMID: 16943268
  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    During embryonic development, expressed in the middle primitive streak and Hensen's node. Expressed in the peripheral region of the developing eye. Expressed in the presomitic mesoderm during somitogenesis in a NOTCH-dependent manner.
  • 数据库链接：

    KEGG: gga:419088

    STRING: 9031.ENSGALP00000001104

    UniGene: Gga.43824