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  4. Recombinant DAZ protein 1 (daz-1)

Recombinant DAZ protein 1 (daz-1)

  • 货号：
    CSB-YP631333CXY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP631333CXY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP631333CXY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP631333CXY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP631333CXY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    daz-1
  • Uniprot No.：
  • 别名：
    daz-1; F56D1.7DAZ protein 1
  • 种属：
    Caenorhabditis elegans
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-499
  • 氨基酸序列
    MMSPPLRYQK DQQNQQHQQN QSQQAAHQMV SFMPQTPTSL PSTPIQLYPT GAAALIPAPP TYELIPNRIF VGGFPTSTTE TELREHFEKF FAVKDVKMVK SLDGQSKGYG FITFETEDQA EEIRKLTPKQ LEFRSRKLNL GPAIRKINSN SFQPSYAIAT PSQLVAASPG PFSYAIPASP SPYSGYSYPA SPQMFVYPPL RSQDQSRQQS EQQTTPQNSP TNLQHQQSPQ VFFGGDQDPI RSYASAVAGV EKSEVSPEKH ESVSPQPLLP NQNVLNTQYS QGQQQWNSNV QQQQQQQMDS NNGGPYYNEN YSQGYTRPHP YQQFAQSGVY MNSQGMYHSS YSYMTPPLAP GQYPQMMSAP YWQQQQQHHQ SHAYAGYNPA YNNWVGPSGD MNQFKQNPSN YFYQNYPGNF SQQHTMGNNE NTFSLPLQAP RQGKKSRKPS ECQDKKTKSP IKGARTERPS SSASTPDAKY QKNHRYPVHL SPLSASLQSL AISSPTKNN
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    RNA-binding protein that plays a central role in oogenesis, but not for spermatogenesis. Required for meiotic entry and germline differentiation, at the pachytene stage of meiosis I of female germline regardless of the sex of the soma. May act by regulating translation of specific mRNAs, possibly by binding to their 3'-UTR.
  • 基因功能参考文献：
    1. DAZ-1 in C. elegans plays essential roles in female premeiotic and early meiotic germ cells, probably via regulating the translational activity of specific target genes required for the progression of oogenesis. PMID: 15572146
    2. daz-1 plays a role upstream of the pathway for germ cell sex determination. PMID: 16641369
    3. in a two hybrid assay,daz- as bait interacted with cpb-3 PMID: 16678151
    4. all germline samples studied were found to be free from AZFc microdeletions and CNP of the DAZ genes. PMID: 17308897
  • 蛋白家族：
    RRM DAZ family
  • 组织特异性：
    Germline specific. More strongly expressed during oogenesis than during spermatogenesis. During the larval stages, it is more abundant at the distal region than the proximal region of the gonad. In young adult hermaphrodites, it is expressed at a very low
  • 数据库链接：

    KEGG: cel:CELE_F56D1.7

    STRING: 6239.F56D1.7

    UniGene: Cel.6835