Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Danio rerio Homeobox protein orthopedia B (otpb)

Recombinant Danio rerio Homeobox protein orthopedia B (otpb)

  • 货号：
    CSB-YP732227DIL
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP732227DIL
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP732227DIL-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP732227DIL
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP732227DIL
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    otpb
  • Uniprot No.：
  • 别名：
    otpb; otp; otp1; otpa; Homeobox protein orthopedia B
  • 种属：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-315
  • 氨基酸序列
    MLSHADLLDT RLGMKDAAAE LLVHREALKC RLGGTDSGHP GDLTSATETV EGTTLLPGEE ISNGGSNPNG MQQVNAKDQE KQQQQNSNQT GGQQNQQKQK RHRTRFTPAQ LNELERSFAK THYPDIFMRE ELALRIGLTE SRVQVWFQNR RAKWKKRKKT TNVFRAPGTL LPTHGLPQFP SAAAAAMGDS LCSFHANDTR WAAAGMPGVS QLQIPPSLGR QQAMAQSLSQ CSLGAGPPPN NMGLSGSLSS NGSGLQSHLY QPTFPGMVPA SLSGPTNVTG SPQLCSSPDS DMWRGTSIAS LRRKALEHTV SMSFT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the specification of isotocin cells. Required for the specification of dopaminergic neurons in the developing hypothalamus and posterior tuberculum.
  • 基因功能参考文献：
    1. These findings reveal a new role for Otp in controlling developmental neuropeptide balance in a discrete oxytocinergic hypothalamic circuit whose disrupted development affects social behavior. PMID: 28094761
    2. Identification of an evolutionarily conserved vertebrate OTP enhancer module with activity in a restricted area of the forebrain. PMID: 25427861
    3. These observations suggest that the requirement for otpa and otpb function during development of the larval diencephalon is partially redundant. PMID: 24073233
    4. Otp1 transcription factor is important for regulation of diencephalon development and early neuronal progenitors. PMID: 17074092
    5. Orthopedia is one of the few known transcription factors that can determine aspects of the dopaminergic phenotype and the first known factor to control the development of the diencephalospinal dopaminergic system. PMID: 17481897
    6. Results describe the ontogeny of vasotocin-expressing cells in zebrafish, and the selective requirement for the transcriptional regulators orthopedia and single-minded 1 in the preoptic area. PMID: 18330923

    显示更多

    收起更多

  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Paired homeobox family, Bicoid subfamily
  • 组织特异性：
    Isoform 1 and isoform 2 are expressed in brain and testis.
  • 数据库链接：

    KEGG: dre:30316

    STRING: 7955.ENSDARP00000122985

    UniGene: Dr.81295