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  4. Recombinant Danio rerio NAD-dependent protein deacetylase sirtuin-2 (sirt2)

Recombinant Danio rerio NAD-dependent protein deacetylase sirtuin-2 (sirt2)

  • 货号：
    CSB-YP767238DIL
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP767238DIL
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP767238DIL-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP767238DIL
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP767238DIL
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    sirt2
  • Uniprot No.：
  • 别名：
    sirt2; zgc:77003; NAD-dependent protein deacetylase sirtuin-2; EC 2.3.1.286; Regulatory protein SIR2 homolog 2; SIR2-like protein 2
  • 种属：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-379
  • 氨基酸序列
    MSEEVSKRVE EEADTPGLEG QSDDSSDEGD ASGDTEMDFL RSLFSRTLGL SPGDKVLDEL TLDSVARYIL SGKCKNIICM VGAGISTSAG IPDFRSPGTG LYANLQKYNL PYPEAIFQID YFKKHPEPFF ALARELYPGQ FKPTVYHYFI KMLKDKGLLR RCYSQNIDTL ERVAGLEGED LIEAHGTFHT SHCVSFLCRK EYSMDWMKNQ IFSEEIPKCD SCGSLVKPDI VFFGESLPSR FFTSMKADFP QCDLLIIMGT SLQVQPFASL VSRVSNRCPR LLINMEKTGQ SEFGMGLFSF GGGMDFDSDK AYRDVAHLST CDDGCMTLAE LLGWKKELEE MVKREHALID SKDAKKTDKE ASQSSKSAVA EAEKTDKTE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors. Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Deacetylates histone H4 at 'Lys-16' (H4K16ac) at the VEGFA promoter. Thereby contributes to regulate expression of vegfa, a key regulator of angiogenesis.
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Sirtuin family, Class I subfamily
  • 数据库链接：

    KEGG: dre:322309

    STRING: 7955.ENSDARP00000003412

    UniGene: Dr.13057