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  4. Recombinant Danio rerio T-box transcription factor TBX1 (tbx1)

Recombinant Danio rerio T-box transcription factor TBX1 (tbx1)

  • 货号：
    CSB-YP804295DIL
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP804295DIL
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP804295DIL-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP804295DIL
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP804295DIL
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    tbx1
  • Uniprot No.：
  • 别名：
    tbx1; zgc:136724; T-box transcription factor TBX1; T-box protein 1
  • 种属：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-460
  • 氨基酸序列
    MISAISSPWL TQLSHFCDVA AFTTSSLSSL NTPGSYHLSP SPGDPYSHHE SQFEPCPAAQ HAYNYSGSNS AQAPAQGDSG TSNCSSSSSS STPNKTLVKK NPKVANINVQ LEMKALWDEF NQLGTEMIVT KAGRRMFPTF QVKIFGMDPM ADYMLLMDFL PVDDKRYRYA FHSSSWLVAG KADPATPGRV HYHPDSPAKG AQWMKQIVSF DKLKLTNNLL DDNGHIILNS MHRYQPRFHV VYVDPRKDSE KYAEENYKTF VFEETRFTAV TAYQNHRITQ LKIASNPFAK GFRDCDPEDW PRNHRPGSLQ IMSAFARTRN PMSSPPQQNG TEKEDSRREY DRDPSGNPLH SDPTHQLMSR VLSPALPVLG GLHAVPLTAG PRSPPHELRL DGHPQPPDTL HHHPYKYPAT YEHYLGAKTR PSPYPSPSIR GHGYHPHMNP TTANMYSATS APTNYDYGPR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable transcriptional regulator involved in developmental processes. Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence. Is required for normal development of the pharyngeal arch arteries. Acts cell autonomously in the pharyngeal mesendoderm and influences the development of neural crest-derived cartilages secondarily.
  • 基因功能参考文献：
    1. Conservation of Tbx1 function in zebrafish second heart field biology. PMID: 23335360
    2. Tbx1 might play an essential role in the development of pharyngeal neural crest cells in zebrafish. Cardiac performance is impaired by Tbx1 knock down in zebrafish. PMID: 20529560
    3. Retinoic acid could produce an altered Tbx1 expression pattern in zebrafish embryos. PMID: 17706063
    4. This newly identified tbx1 expression pattern in cardiac regions other than the cardiac outflow tract offers a new insight into the role of the tbx1 transcription factor in cardiac development. PMID: 12972000
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Expressed in the ear and mesendodermal components of pharyngeal arches.
  • 数据库链接：

    KEGG: dre:368206

    STRING: 7955.ENSDARP00000118808

    UniGene: Dr.78157