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  4. Recombinant Dog Insulin-like 3 (INSL3)

Recombinant Dog Insulin-like 3 (INSL3)

  • 货号：
    CSB-YP747685DO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP747685DO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP747685DO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP747685DO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP747685DO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    INSL3
  • Uniprot No.：
  • 别名：
    INSL3; RLFInsulin-like 3; Leydig insulin-like peptide; Ley-I-L; Relaxin-like factor) [Cleaved into: Insulin-like 3 B chain; Insulin-like 3 A chain]
  • 种属：
    Canis familiaris (Dog) (Canis lupus familiaris)
  • 蛋白长度：
    Cytoplasmic domain
  • 表达区域：
    25-58
  • 氨基酸序列
    SAPAPG AREKLCGHHF VRALVRVCGG PRWSSEDG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.
  • 基因功能参考文献：
    1. work provides evidence of the immunolocalisation of isulin-like 3 (INSL3) in the Leydig cells of canine fetuses and of the expression of relaxin/insulin-like family peptide receptor 2(RXFP2) in different tissues of the gubernaculum testis PMID: 20450827
    2. isolation and analysis of full-length canine INSL3 gene; isolated the promoter and showed that its activity was strongly mediated by steroidogenic factor-1 in vitro; identified a well-conserved steroidogenic factor-1 binding site within the INSL3 promoter PMID: 12890727
    3. The aim of this work was to study the presence and distribution of INSL3 in the dog fetal testis, and the possible expression of the RXFP2 receptor in the same animals. PMID: 19585260
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Insulin family
  • 组织特异性：
    More strongly expressed in testis than in ovary.
  • 数据库链接：

    KEGG: cfa:403436

    STRING: 9615.ENSCAFP00000041498

    UniGene: Cfa.139