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  4. Recombinant Drosophila equinoxialis Period circadian protein (per)

Recombinant Drosophila equinoxialis Period circadian protein (per)

  • 中文名称：
    Recombinant Drosophila equinoxialis Period circadian protein(per),Yeast
  • 货号：
    CSB-YP309359DFY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Drosophila equinoxialis Period circadian protein(per),Yeast
  • 货号：
    CSB-EP309359DFY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Drosophila equinoxialis Period circadian protein(per),Yeast
  • 货号：
    CSB-EP309359DFY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Drosophila equinoxialis Period circadian protein(per),Yeast
  • 货号：
    CSB-BP309359DFY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Drosophila equinoxialis Period circadian protein(per),Yeast
  • 货号：
    CSB-MP309359DFY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    per
  • Uniprot No.：
  • 别名：
    perPeriod circadian protein; Fragment
  • 种属：
    Drosophila equinoxialis (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-395
  • 氨基酸序列
    SSTETPPSYN QLNYNENLLR FFNSKPVTAP VELDPPKVES SYVSSARGED ARSTLSPVQG FEGSGGSGSS GNFTTGSNLH MSSVTNTSNA GTGTSGTGNS GDGGGGGGAD GTGSGAAPPV TLTESLLNKH NDEMEKFMLK KHRESRGRSG EKNKKSANEA MKMLEYSGPG PGHGHGIKRG GSHSWEGEAN KPKQQLTLNT SGGGGGGGGG GGMPLFLDMT HASSSSQNKG LAGVGVGGAG GVVGGGSGTG LGGNGNVGSG NGNNNQPSTN QYTQSRLPCT QNINLWPPFS VGITTPTSVL SSHTAVPPSS FSPQHSLFPT FYYIPASIAA SSPSGTNTNP NRPHKHAHVH NSSEKPSTSQ AAAATMPLQY MTGVMYPHPS LFYTHPAAAA ATAMV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Essential for biological clock functions. Determines the period length of circadian and ultradian rhythms; an increase in PER dosage leads to shortened circadian rhythms and a decrease leads to lengthened circadian rhythms. Essential for the circadian rhythmicity of locomotor activity, eclosion behavior, and for the rhythmic component of the male courtship song that originates in the thoracic nervous system. The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex. Light induces the degradation of TIM, which promotes elimination of PER. Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop. Behaves as a negative element in circadian transcriptional loop. Does not appear to bind DNA, suggesting indirect transcriptional inhibition.
  • 亚细胞定位：
    Nucleus. Cytoplasm, perinuclear region.