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  4. Recombinant Drosophila melanogaster Allatostatins MIP (Mip)

Recombinant Drosophila melanogaster Allatostatins MIP (Mip)

  • 中文名称：
    黑腹果蝇Mip重组蛋白
  • 货号：
    CSB-YP892903DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇Mip重组蛋白
  • 货号：
    CSB-EP892903DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇Mip重组蛋白
  • 货号：
    CSB-EP892903DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇Mip重组蛋白
  • 货号：
    CSB-BP892903DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇Mip重组蛋白
  • 货号：
    CSB-MP892903DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Mip
  • Uniprot No.：
  • 别名：
    Mip; CG6456; Allatostatins MIP; B-type Allostatin preprohormone; Myoinhibitory-like protein) [Cleaved into: Drostatin-B1; MIP-1); Drostatin-B2; MIP-2); Drostatin-B3; MIP-3); Drostatin-B4; MIP-4); Drostatin-B5; MIP-5)]
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Cytoplasmic domain
  • 表达区域：
    66-74
  • 氨基酸序列
    AWQSL QSSW
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Ligand for the sex peptide receptor (SPR). Stabilizes sleep and maintains sleep homeostasis to inhibit the activity of wake-promoting circuits, such as those that involve the pigment dispersing factor (pdf) neurons. Regulated by the circadian clock network and pathways associated with a sleep homeostat. May also have a regulatory role in gut motility.
  • 基因功能参考文献：
    1. Mip neuropeptides appear to promote mating receptivity both in virgins and mated females, although it is dispensable for normal mating in virgin females. PMID: 29158481
    2. MIP signaling in chemosensory neurons is an instructive signal adjusting female choice behavior to reproductive state. PMID: 27145127
    3. MIP encodes anorexigenic brain signaling that determines body weight.MIP produces satiety responses independently of sex peptide receptor.MIP modulates behavioral responses to olfactory and gustatory cues of food. PMID: 26948873
    4. Our results illuminate how cell type specific versions of the Mip/dREAM complex and the general transcription machinery cooperate to drive selective gene activation during differentiation in stem cell lineages. PMID: 26624996
    5. released centrally before and during night-time sleep, when the sleep drive is elevated PMID: 25333796

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  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    In larvae, strongly expressed in the midgut region before and in between the copper cells, and in a group of cells in the posterior part of the larval midgut. Expressed in the neurons of many areas including the subesophageal ganglion/tritocerebrum (SOG),
  • 数据库链接：

    KEGG: dme:Dmel_CG6456

    STRING: 7227.FBpp0075003

    UniGene: Dm.4361